Results 51 to 60 of about 313,676 (255)

Bridging foundations and frontiers in responsible innovation: a quantitative map of knowledge bases and emerging themes

Journal of Responsible Innovation
As Responsible Innovation (RI) principles are applied to frontier areas such as emerging technologies, a key question is whether this expansion reflects deep integration of RI’s core commitments or surface-level adoption.
Yuwen Xu, Suzana Sampaio, Kathryn Cormican   +2 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Establishing circularity: development and validation of the circular work value scale (CWVS)

Frontiers in Psychology
ObjectivesAddressing the lack of German-language instruments, this study aims to develop a questionnaire that enables the measurement of work values. According to the theory of basic human values (Schwartz, 1992), a culturally fitting questionnaire is ...
Jannick Schneider, Jannick Schneider, Clemens Striebing, Katharina Hochfeld, Timo Lorenz   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

The fragility of responsibility. norway’s transformative agenda for research, innovation and business, Edited by Giovanni De Grandis and Anne Blanchard, volume 9 of De Gruyter studies in innovation and entrepreneurship, an open access publication

Journal of Responsible Technology
This is a review of The Fragility of Responsibility. Norway’s Transformative Agenda for Research, Innovation and Business, Edited by Giovanni De Grandis and Anne Blanchard, which describes Norwegian approaches to addressing responsibility in innovation ...
Jonathan Hankins
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

A New Bet for Scientists? Implementing the Responsible Research and Innovation (RRI) approach in the practices of research institutions

Relations, 2017
In last years, the European Commission has promoted an approach that seeks to anticipate and assess potential implications and societal expectations with regard to research and innovation, with the aim to foster the “design of inclusive and sustainable ...
Alba L’Astorina, Monica Di Fiore
doaj   +1 more source

Organizing as negotiation: the construction of a pathway in Norwegian mental health services

International Journal of Mental Health Systems, 2021
Background In 2015, a decision was made to implement clinical pathways in Norwegian mental health services. The idea was to construct pathways similar to those used in cancer treatment.
Tine Nesboe Toerseth
doaj   +1 more source