Results 51 to 60 of about 1,354,140 (303)

Deliberating stratospheric aerosols for climate geoengineering and the SPICE project [PDF]

, 2013
Increasing concerns about the narrowing window for averting dangerous climate change have prompted calls for research into geoengineering, alongside dialogue with the public regarding this as a possible response.
A Corner, A Corner, A Irwin, A Rip, A Stirling, AP Nielsen, B Wynne, BA Turner, C Hamilton, C Marris, D Bhattachary, D Fiorino, DH Guston, HD Matthews, HJ Buck, J Brown, J Chilvers, J Chilvers, J Lezaun, JS Dryzek, K Bickerstaff, K Parkhill, M Callon, M Philbrick, MD Cobb, NE Vaughan, NF Pidgeon, NF Pidgeon, NF Pidgeon, NF Pidgeon, NF Pidgeon, O Renn, O Renn, P Harremoës, P Macnaghten, P Macnaghten, R Owen, RV Burri, S Jasanoff, S Rayner, SM Gardiner, T Dietz, T Rogers-Hayden   +42 more
core   +2 more sources

Financial Burden Associated With Hospitalisation Among Families of Childhood Brain Tumours in Australia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim, Natalie Bradford, David Brain, Sameera Senanayake, Sanjeewa Kularatna, Kate Young, Christine Cashion, Tim Hassall, Susanna Cramb   +8 more
wiley   +1 more source

Report on Responsible Research and Innovation (RRI) Workshop [PDF]

, 2015
The potential for an ongoing interdisciplinary conversation about RRI at the University of Nottingham (UoN) was identified during a research project conducted in summer 2014 to investigate how RRI is being interpreted within UoN (Pearce et al., 2014 ...
Hadley Kershaw, Eleanor, Hartley, Sarah, Pearce, Warren   +2 more
core  

The EPSRC's policy of responsible innovation from a trading zones perspective [PDF]

, 2016
Responsible innovation (RI) is gathering momentum as an academic and policy debate linking science and society. Advocates of RI in research policy argue that scientific research should be opened up at an early stage so that many actors and issues can ...
Murphy, Joseph, Parry, Sarah, Walls, John   +2 more
core   +3 more sources

Feasibility and Preliminary Efficacy of Integrative Neuromuscular Training for Childhood Cancer Survivors: A Pilot Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian, Robert U. Newton, Dennis R. Taaffe, Nicholas G. Gottardo, Santosh Valvi, Carolyn J. Peddle‐McIntyre, Jodie Cochrane Wilkie, Daniel A. Galvão   +7 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Responsibility versus sustainability, ethics, and societal engagement

TATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, 2020
We examine the concept of responsible research and innovation (RRI) in Germany in the context of national science, technology and innovation (STI) as well as its legal and normative framework in relation to ethics and societal engagement and compare the ...
Miltos Ladikas, Julia Hahn, Leonhard Hennen, Constanze Scherz   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Responsible Research and Innovation in Enterprises: Benefits, Barriers and the Problem of Assessment

Journal of Open Innovation: Technology, Market and Complexity, 2020
In the paper, the author takes stock of the conceptual reflection and empirical studies described in the current scientific literature on responsible innovation in the context of the emergence of the Responsible Research and Innovation (RRI) concept. RRI
Lukasz Nazarko
doaj   +1 more source