Results 91 to 100 of about 1,207,951 (297)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Psicologia: Reflexão e Crítica, 2007 The study aimed at investigating the impact of children temperament, maternal responsiveness and maternal childrearing practices on children externalizing behavior problems and social competence.
Patrícia Alvarenga, Cesar A. Piccinini
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Scandinavian Journal of Work, Environment & Health, 2015 OBJECTIVES: The aims of the present study were to (i) cross-culturally adapt a Danish consensus version of the 10-item Perceived Stress Scale (PSS-10) and (ii) evaluate its psychometric properties in terms of agreement, reliability, validity ...
Anita Eskildsen +7 more
doaj +1 more source
Transportation decisions of small businesses in Soweto: Balancing responsiveness and efficiency
Journal of Transport and Supply Chain Management, 2016 Background: The performance of small businesses makes an important contribution to the South African economy. Although the South African government implemented various initiatives for the development of small businesses in townships, the full advantage ...
Themari Eicker, Jacoba O. Cilliers
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Payesh, 2017 Objective (s): Data collection is one of the important stages of research process and requires valid and reliable instruments. The aim of this article was to introduce important steps of translation and construction process of a questionnaire.
Abbas Ebadi +5 more
doaj
Learning a musical instrument: the influence of interpersonal interaction on outcomes for school-aged pupils [PDF]
, 2011 Researchers in recent years have increasingly placed an emphasis on seeking pupils' perceptions of educational settings. Alongside this shift towards attaching value to the pupil viewpoint has been a growing interest concerning how interpersonal ...
Creech, Andrea, Hallam, Susan
core +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Frontiers in Psychology, 2016 Team coordination implies a system of individual behavioral contributions occurring within a network of interpersonal relationships to achieve a collective goal.
John Paul Stephens +1 more
doaj +1 more source