Results 101 to 110 of about 1,207,951 (297)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
ASAP: The After Salesman Problem [PDF]
The customer contacts taking place after a sales transaction and the services involved are of increasing importance in contemporary business models. The responsiveness to service requests is a key dimension in service quality and therefore an important ...
Klundert, Joris van de, Wormer, Laurens
core +1 more source
RESPONSE: A Solemn Responsibility
Journal of the American College of Cardiology, 2018 Dr. Han writes a thoughtful perspective on the opioid epidemic and its evident impact on organ donation. While I too share his discomfort knowing that many of the overdose deaths are preventable, this narrative is not new.
openaire +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Developing an Index to Measure the Value of Health Care Provided to Stroke Patients
Annals of Indian Academy of NeurologyBackground and Objectives: It is possible to evaluate health services for stroke patients based on clinical benefits. However, in recent years, questions about responsiveness and outcomes have also emerged.
Halil Şengül +3 more
doaj +1 more source
Development and initial validation of the ibadan knee/hip osteoarthritis outcome measure
South African Journal of Physiotherapy, 2007 Background and Aim: Development of outcome measures remains a focus of health research in the 21st century. Outcome measures originally developed for the Nigerian environment are very rare.
A. O. Akinpelu +3 more
doaj +1 more source
A Brief Version of the Family Background Questionnaire [PDF]
, 2009 Although it is lengthy. the Family Background Questionnaire provides reliable behaviorally specific family history information. Results from reliability and validity analyses suggest that a brief version of this instrument that assesses parental ...
Kalemeera, Augustine +1 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source