Results 1 to 10 of about 48,163 (143)

Structure-Function Relationship of the Disintegrin Family: Sequence Signature and Integrin Interaction

Frontiers in Molecular Biosciences, 2021
Disintegrins are small cysteine-rich proteins found in a variety of snake venom. These proteins selectively modulate integrin function, heterodimeric receptors involved in cell-cell and cell-matrix interaction that are widely studied as therapeutic ...
Ariana A. Vasconcelos, Ariana A. Vasconcelos, Jorge C. Estrada, Victor David, Luciana S. Wermelinger, Fabio C. L. Almeida, Fabio C. L. Almeida, Russolina B. Zingali   +7 more
doaj   +1 more source

Hipotensão intracraniana espontânea.

Acta Médica Portuguesa, 2001
The authors consider some clinical and radiological aspects of spontaneous intracranial hypotension syndrome, based on the knowledge obtained from three clinical situations. Postural headache was a constant complaint.
J Graça, C Conceição, T Palma, C Barroso, C Ribeiro, P Evangelista   +5 more
doaj   +1 more source

Glifosato: um problema da ciência e da tecnologia para a sociedade

Indagatio Didactica, 2019
Numa definição inicial - sempre é possível se complexificar as definições - podemos dizer que a Química é a ciência que estuda as substâncias, suas transformações e as energias envolvidas nelas. Daí depreende-se que o conceito de Reação Química é central
Andressa Kuhnen Silva, Luciano Morais Lião, Simone Maria Teixeira de Sabóia-Morais, Francisco Gambarra Neto, Agustina Rosa Echeverría   +4 more
doaj   +1 more source

Ressonância Magnética fetal.

Acta Médica Portuguesa, 2001
The increasing use of magnetic resonance imaging (MRI) in fetal evaluation is due to its excellent structural and morphological resolution. We report nine fetal MRI examinations and discuss some of the technical issues related to this technique.We report
P Vilela, J Duarte, A Goulão
doaj   +1 more source

Estudo por ressonância magnética do fluxo aquedutal em doentes com hidrocefalia pressão normal.

Acta Médica Portuguesa, 2001
The treatment of patients with the so-called Normal Pressure Hydrocephalus (NPH) consists of ventricular shunting, but only in some cases is there clinical improvement.
S Matias, T Ferreira, P Vilela, M Secca, A Goulão   +4 more
doaj   +1 more source

Reconstruções tridimensionais cerebrais por Ressonância Magnética. Importância no planeamento neurocirúrgico.

Acta Médica Portuguesa, 2001
The authors describe their experience with three-dimensional (3D) MRI reconstructions of the cerebral cortex in neurosurgical planning of cortical and subcortical lesions.
T Palma, I Cravo, C Conceição, J Graça, P Evangelista, C Ribeiro, M Secca   +6 more
doaj   +1 more source

Aplicações pré-cirúrgicas do mapeamento cortical por Ressonância Magnética Funcional.

Acta Médica Portuguesa, 2001
The authors describe a clinical experience in cortical brain mapping by Functional Magnetic Resonance Imaging (FMRI) with a 1.0 T MR scanner with BOLD technique and echo-planar imaging (EPI).
I Cravo, T Palma, C Conceição, P Evangelista   +3 more
doaj   +1 more source

Doença cérebro-vascular na gravidez e no puerpério.

Acta Médica Portuguesa, 2001
Cerebrovascular diseases are the main causes of neurological events occurring during pregnancy and puerperium.We retrospectively reviewed the clinical records and imaging scans of females presenting with stroke during pregnancy or puerperium. We selected
P Vilela, J Duarte, A Goulão
doaj   +1 more source

Amide hydrogens reveal a temperature-dependent structural transition that enhances site-II Ca2+-binding affinity in a C-domain mutant of cardiac troponin C

Scientific Reports, 2017
The hypertrophic cardiomyopathy-associated mutant D145E, in cardiac troponin C (cTnC) C-domain, causes generalised instability at multiple sites in the isolated protein.
Tiago Veltri, Guilherme A. P. de Oliveira, Ewa A. Bienkiewicz, Fernando L. Palhano, Mayra de A. Marques, Adolfo H. Moraes, Jerson L. Silva, Martha M. Sorenson, Jose R. Pinto   +8 more
doaj   +1 more source

Structural connectivity of the brain: differences between a normal brain and a brain with pathology

Saúde & Tecnologia, 2015
Understanding the large-scale structural network formed by neurons is a major challenge in neuroscience. In this study we analyzed the structural connectivity of the human brain in 22 healthy subjects and in two patients with post-traumatic epilepsy.
Carmen Ferra, Hugo Alexandre Ferreira, Pedro Gonçalves Pereira, Rui Manaças, Alexandre Andrade   +4 more
doaj   +1 more source