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ВЫБОР ВЕБ-ТЕХНОЛОГИИ ДЛЯ ИНТЕГРАЦИИ С ПЛАТФОРМОЙ «1С: ПРЕДПРИЯТИЯ 8»

Cifra: Информационные технологии и телекоммуникации
В статье разобраны способы интеграции платформы «1С: Предприятие 8» с веб-технологиями для создания альтернативного пользовательского интерфейса, разрешающего задачи, возникающие у предприятия: реализация интерфейса для работы сотрудников и разработка ...
Ширяев А.И.
doaj   +1 more source

DIRAC RESTful API

Journal of Physics: Conference Series, 2012
The DIRAC framework for distributed computing has been designed as a flexible and modular solution that can be adapted to the requirements of any community. Users interact with DIRAC via command line, using the web portal or accessing resources via the DIRAC python API. The current DIRAC API requires users to use a python version valid for DIRAC.
Casajus Ramo, A., Graciani Diaz, R., Tsaregorodtsev, A.   +2 more
openaire   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Microservices implementation using Rest API for MSMEs based on Raspberry PI

Sistemasi: Jurnal Sistem Informasi
Micro, Small and Medium Enterprises (MSMEs) are business activities that are able to expand employment opportunities and provide broad economic services to the community. The role of digital technology has increased significantly to assist activities and
Norma Ningsih, Nailul Muna, Faridatun Nadziroh   +2 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Integración de la API de ChatGPT para optimizar la interacción Usuario-Máquina mediante consultas estructuradas

Informes Científicos y Técnicos (Universidad Nacional de la Patagonia Austral)
La formulación de consultas ambiguas en plataformas como ChatGPT limita la efectividad de los sistemas de inteligencia artificial para generar respuestas relevantes y precisas.
Lucas GOROSITO, Sandra CASAS
doaj   +3 more sources

Secure and Modular Data Portal: Database System to Manage Broadly Classified and Large Scale Data

Data Science Journal
Using various types of broadly classified and large-scale datasets, Ethiopian Construction Design and Supervision Works Corporation (ECDSWC) provides professional services such as engineering studies and design.
Atnafu Abrham Lencha, Addisalem Bitew Mitiku, Abel Tadesse Woldemichael   +2 more
doaj   +1 more source