Results 71 to 80 of about 22,449 (264)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

REST compliant clients for REST APIs

, 2015
In today's distributed systems, REST services play a centric role in defining applications' architecture. Current technologies and literature focus on building server-side REST applications. But they fail to build generic and REST compliant client solutions.
openaire   +3 more sources

Penerapan REST API pada Aplikasi Antarmuka Alat Pemantauan Tambak Udang

Journal of Applied Computer Science and Technology
Increasing shrimp pond productivity is a top priority in fisheries cultivation, especially with the challenge of maintaining water quality as a determining factor for success.
Fiqri Abdul Aziz, M. Asep Subandri, Armada   +2 more
doaj   +1 more source

A Cloud Service Architecture for Analyzing Big Monitoring Data

Tsinghua Science and Technology, 2016
Cloud monitoring is of a source of big data that are constantly produced from traces of infrastructures, platforms, and applications. Analysis of monitoring data delivers insights of the system’s workload and usage pattern and ensures workloads are ...
Samneet Singh, Yan Liu
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Laravel framework and native PHP: Comparison in the creation of rest API

Matrix: Jurnal Manajemen Teknologi dan Informatika
As technology evolves, the need for data communication grows. One technology facilitating this communication between applications and databases is the REST API, widely used by companies to provide access to their data and services.
Yuri Ariyanto, Mochamad Farhan Fitrahtur Rachmad, Dwi Puspitasari   +2 more
doaj   +1 more source

Improving Performance through REST Open API Grouping for Wireless Sensor Network

International Journal of Distributed Sensor Networks, 2013
With this growth of the Internet, it is expected that every device, including computers, will be connected to the Internet, as it is called IoT. For example, smartphones and even refrigerators require an address to connect to the Internet.
Min Choi, Young-Sik Jeong, Jong Hyuk Park   +2 more
doaj   +1 more source

Creation of an automated information system using Python and the Django framework with a telegram bot [PDF]

Big Data and Computing Visions
This article presents the development of an automated Information System (IS) using Python, the Django framework, and a Telegram bot. The system processes user requests through a chatbot interface, providing data management and retrieval functionalities ...
Khojiakbar Egamberdiev, Noila Khidirova, Abram Islomov   +2 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source