Results 21 to 30 of about 46,297 (193)

Pathway analysis using genome-wide association study data for coronary restenosis--a potential role for the PARVB gene.

PLoS ONE, 2013
BackgroundCoronary restenosis after percutaneous coronary intervention (PCI) still remains a significant limitation of the procedure. The causative mechanisms of restenosis have not yet been fully identified.
Jeffrey J W Verschuren, Stella Trompet, M Lourdes Sampietro, Bastiaan T Heijmans, Werner Koch, Adnan Kastrati, Jeanine J Houwing-Duistermaat, P Eline Slagboom, Paul H A Quax, J Wouter Jukema   +9 more
doaj   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

In-Stent Ulceration: An Unusual Pathology

Case Reports in Cardiology, 2014
In-stent restenosis occurs in 10–60% of cases undergoing interventional therapy. Many mechanisms explain the reason for in-stent restenosis, but restenosis due to an ulcerated plaque is very rare and has not been well reported in the literature.
Jagadeesh Kumar Kalavakunta, Shravan Gangula, Vishal Gupta   +2 more
doaj   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

A Bespoke Programmable Interpenetrating Elastomer Network Composite Laryngeal Stent for Expedited Paediatric Laryngotracheal Reconstruction

Advanced Functional Materials, EarlyView.
A programmable interpenetrating double‐network architecture, created via 3D‐TIPS printing and resin infusion, synergistically combines thermoplastic and thermosetting elastomers to balance structural rigidity and surface softness—crucial for paediatric laryngeal stents.
Elizabeth F. Maughan, Lei Wu, Dong Zhang, Linxiao Wu, Graca Ferreira Vaz Pinto Mendes, Wanqiao J. Tu, Heping Ma, Toby J. Proctor, Colin R. Butler, Thomas Kjærgaard, Mark W. Lowdell, Martin A. Birchall, Robert E. Hynds, Richard Hewitt, Wenhui Song   +14 more
wiley   +1 more source

Clinical condition and cardiovascular risk factors displaying neoatherosclerosis in stented coronary arteries with developing restenosis

Кардиоваскулярная терапия и профилактика, 2016
Aim. To study the significance of clinical parameters and cardiovascular risk factors (CVR) for restenosis development at long terms after percutaneous coronary intervention (PCI) as a possible displaying of neoatherosclerosis development (NA).Material ...
V. P. Mazaev, A. A. Komkov, S. V. Ryazanova   +2 more
doaj   +1 more source

Smart Catheters for Diagnosis, Monitoring, and Therapy

Advanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman, Samiha Ahmed, Majed Othman Althumayri, Megan Guy, Darlenne Chavez Lugo, Frances S. Ligler, George T. Ligler, Rahmi Oklu, Hiroshi Kawahira, Michael J. McShane, Jun Kameoka, Jonathan Bova, Hatice Ceylan Koydemir   +12 more
wiley   +1 more source

High red blood cell distribution width is closely associated with in-stent restenosis in patients with unstable angina pectoris

BMC Cardiovascular Disorders, 2019
Background In-stent restenosis remains an unresolved issue. Inflammation plays a pivotal role in the process of in-stent restenosis. Significant and positive associations were found between red blood cell distribution width (RDW) and inflammation.
Ning Geng, Guangsheng Su, Shaojun Wang, Deling Zou, Wenyue Pang, Yingxian Sun   +5 more
doaj   +1 more source

Diabetes and restenosis

Cardiovascular Diabetology, 2022
Restenosis, defined as the re-narrowing of an arterial lumen after revascularization, represents an increasingly important issue in clinical practice.
Scott Wilson, Pasquale Mone, Urna Kansakar, Stanislovas S. Jankauskas, Kwame Donkor, Ayobami Adebayo, Fahimeh Varzideh, Michael Eacobacci, Jessica Gambardella, Angela Lombardi, Gaetano Santulli   +10 more
doaj   +1 more source

Endothelial Cytotoxicity of Drug‐Doped Polypyrrole Coatings on Biodegradable Iron for Stent Applications

Advanced Materials Interfaces, EarlyView.
Electrochemically deposited polypyrrole coatings doped with salicylate and dexamethasone are tested on iron substrates. Their safety for biological use is confirmed in vitro with human endothelial cells. Abstract Conducting polymers, such as polypyrrole (PPy), are promising coatings for biodegradable vascular implants due to their electrical ...
Karolina Cysewska, Jagoda Litowczenko, Piotr Jasiński   +2 more
wiley   +1 more source