Pathogenetic mechanism of stented coronary arteries restenosis and the role of vasculoendothelial growth factor A [PDF]
The contemporary issue of in-stent restenosis is reviewed in the article. The widespread use of interventional technologies for the treatment of acute and chronic forms of ischemic heart disease led to the appearance of the problem of coronary artery ...
M.P. Kopytsya +2 more
doaj +1 more source
Liraglutide Ameliorates Injury-Related Vascular Repair by Activating Autophagy Through Modulation of the PI3K-mTOR Signaling Pathway. [PDF]
Liraglutide inhibits chronic stress‐induced vascular injury in mice by inhibiting the activation of the PI3K‐mTOR signaling pathway and promoting autophagy of smooth muscle cells or macroautophagy. ABSTRACT Chronic stress is a significant risk factor for postoperative restenosis and other cardiovascular diseases, as it can promote the intimal ...
Zhang Z +14 more
europepmc +2 more sources
BACKGROUND: In-stent restenosis affects long-term outcome in patients with intracranial atherosclerotic stenosis. PURPOSE: The aim of this meta-analysis was to evaluate the incidence and risk factors of in-stent restenosis.
G. Peng, Yang Zhang, Z. Miao
semanticscholar +1 more source
Implantation of paclitaxel-eluting stents in saphenous vein grafts: clinical and angiographic follow-up results from a multicentre study. [PDF]
Objective: To define the clinical and angiographic follow-up results after implantation of paclitaxel-eluting stents (PESs) in stenotic saphenous vein grafts (SVGs). Design: Prospective multicentre study. Comparison with a control group.
Blindt, Ruediger +5 more
core +2 more sources
Pathogen burden, inflammation, proliferation and apoptosis in human in-stent restenosis - Tissue characteristics compared to primary atherosclerosis [PDF]
Pathogenic events leading to in-stent restenosis (ISR) are still incompletely understood. Among others, inflammation, immune reactions, deregulated cell death and growth have been suggested. Therefore, atherectomy probes from 21 patients with symptomatic
Abdelmegui AE +24 more
core +1 more source
Mechanistic evaluation of long-term in-stent restenosis based on models of tissue damage and growth
Development and application of advanced mechanical models of soft tissues and their growth represent one of the main directions in modern mechanics of solids. Such models are increasingly used to deal with complex biomedical problems.
R. He +3 more
semanticscholar +1 more source
Inhibition of in-stent stenosis by oral administration of bindarit in porcine coronary arteries [PDF]
<p><b>Objective:</b> We have previously demonstrated that bindarit, a selective inhibitor of monocyte chemotactic proteins (MCPs), is effective in reducing neointimal formation in rodent models of vascular injury by reducing smooth ...
Baker, A.H. +10 more
core +1 more source
Robust optimization of cardiovascular stents: A comparison of methods [PDF]
This is the post-print version of the Article. The official published version can be accssed from the links below. Copyright @ 2004 Taylor & FrancisModern engineering design contains both creative and analytic components.
Atherton, MA, Bates, RA
core +1 more source
BackgroundIncreasing evidence suggests that insulin resistance is linked to cardiovascular disease and atherosclerosis. The triglyceride–glucose (TyG) index has proven to be a convincing marker to quantitatively evaluate insulin resistance.
Shan-shan Zhao +4 more
doaj +1 more source
A polymer coated cicaprost-eluting stent increases neointima formation and impairs vessel function in the rabbit iliac artery [PDF]
Drug-eluting stents have been successful in reducing in-stent restenosis but are not suitable for all lesion types and have been implicated in causing late stent thrombosis due to incomplete regeneration of the endothelial cell layer.
Jones, Robert L. +4 more
core +2 more sources

