Results 101 to 110 of about 10,073,117 (279)

EEG Resting-State Large-Scale Brain Network Dynamics Are Related to Depressive Symptoms

bioRxiv, 2019
Background The few previous studies on resting-state EEG microstates in depressive patients suggest altered temporal characteristics of microstates compared to those of healthy subjects. We tested whether resting-state microstate temporal characteristics
A. Damborská, M. Tomescu, E. Honzírková, R. Barteček, J. Hořínková, Sylvie Fedorová, Š. Ondruš, C. Michel   +7 more
semanticscholar   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Resting-state functional connectivity of orthographic networks in acquired dysgraphia

Frontiers in Psychology, 2015
Introduction. While task-based fMRI has been used extensively to study the functional neural networks that instantiate cognitive functions, there is increasing interest in analyzing the activity of the brain while it is not performing a task – in the ...
Gali Ellenblum
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Resting state connectivity differences in eyes open versus eyes closed conditions

Human Brain Mapping, 2019
Functional magnetic resonance imaging data are commonly collected during the resting state. Resting state functional magnetic resonance imaging (rs‐fMRI) is very practical and applicable for a wide range of study populations. Rs‐fMRI is usually collected
O. Agcaoglu, T. Wilson, Yu-ping Wang, J. Stephen, V. Calhoun   +4 more
semanticscholar   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

The impact of mental fatigue on brain activity: a comparative study both in resting state and task state using EEG

BMC Neuroscience, 2019
Background Mental fatigue is usually caused by long-term cognitive activities, mainly manifested as drowsiness, difficulty in concentrating, decreased alertness, disordered thinking, slow reaction, lethargy, reduced work efficiency, error-prone and so on.
Gang Li, Shan Huang, Wanxiu Xu, Weidong Jiao, Yonghua Jiang, Zhao Gao, Jianhua Zhang   +6 more
semanticscholar   +1 more source

Loss of intranetwork and internetwork resting state functional connections with Alzheimer\u27s disease progression [PDF]

, 2012
Alzheimer\u27s disease (AD) is the most common cause of dementia. Much is known concerning AD pathophysiology but our understanding of the disease at the systems level remains incomplete.
Ances, Beau M, Benzinger, Tammie L, Brier, Mathew R, Holtzman, David M, Morris, John C, Raichle, Marcus E, Snyder, Abraham Z, Thomas, Jewell B, Zhang, Dongyang   +8 more
core   +2 more sources

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Task vs. Rest - Different Network Configurations between the Coactivation and the Resting-State Brain Networks

Frontiers in Human Neuroscience, 2013
There is a growing interest in studies of human brain networks using resting-state functional magnetic resonance imaging (fMRI). However, it is unclear whether and how brain networks measured during the resting-state exhibit comparable properties to ...
Xin eDi, Suril eGohel, Eun H Kim, Bharat B Biswal   +3 more
doaj   +1 more source