Results 51 to 60 of about 17,837,860 (297)
BMC Medical ImagingObjective This study seeks to identify brain regions with atypical neural connectivity in individuals suffering from arthritis-related chronic pain, compared to healthy controls, using resting-state functional magnetic resonance imaging (rs-fMRI ...
Belfin Robinson +7 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Evaluating the Use of Entropy Field Decomposition in Resting State Functional Magnetic Resonance Imaging Analysis [PDF]
, 2017 The study of resting state functional magnetic resonance imaging (rs-fMRI) data has been the subject of increasing academic interest over the past decade.
Parmar, Nishaal
core
NeuroImage: Clinical, 2019 Localizing neurologic function within the brain remains a significant challenge in clinical neurosurgery. Invasive mapping with direct electrocortical stimulation currently is the clinical gold standard but is impractical in young or cognitively delayed ...
Jarod L. Roland +7 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Resting-state network organisation in children with traumatic brain injury
, 2023 Children with traumatic brain injury are at risk of neurocognitive and behavioural impairment. Although there is evidence for abnormal brain activity in resting-state networks after TBI, the role of resting-state network organisation in paediatric TBI ...
C C Kooper (13309017) +6 more
core
Caratterizzazione delle metriche di grafo applicate alle mappe di connettività funzionale in resting-state [PDF]
, 2022 Il resting-state è uno stato cerebrale di particolare interesse. lo studio affrontato con risonanza magnietica funzionale ha previsto l'analisi di grafo per rendere robuste le mappe di connettivita ...
Digiacomo, Francesca
core
Ageing and the resting state: is cognition obsolete? [PDF]
Language, Cognition and Neuroscience, 2016 Recent years have seen the rise in popularity of the resting state approach to neurocognitive aging, with many studies examining age differences in functional connectivity at rest and relating these differences to cognitive performance outside the scanner.
Karen L, Campbell, Daniel L, Schacter
openaire +2 more sources
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source