Results 81 to 90 of about 10,073,117 (279)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Spontaneous Associations under Mild Compression of the Hippocampal Area

Вестник Московского университета. Серия 14: Психология
Background. The network principle of cognitive phenomena implementation in the brain presupposes self-organization of distributed neuronal elements into a network for processing information demanded by the organism at a given moment.
Olga A. Krotkova , Arina N. Kiseleva , Alesia S. Bichkova , Mariya U. Kaverina   +3 more
doaj   +1 more source

Sex Classification by Resting State Brain Connectivity

bioRxiv, 2019
A large amount of brain imaging research has focused on group studies delineating differences between males and females with respect to both cognitive performance as well as structural and functional brain organization.
S. Weis, K. Patil, F. Hoffstaedter, Alessandra, Nostro, B. T. T. Yeo, S. Eickhoff   +6 more
semanticscholar   +1 more source

Fractal analysis of resting state functional connectivity of the brain [PDF]

, 2012
A variety of resting state neuroimaging data tend to exhibit fractal behavior where its power spectrum follows power-law scaling. Resting state functional connectivity is significantly influenced by fractal behavior which may not directly originate from ...
Achard, Sophie, Brückner, Bernd, Seiffert, Udo, Stadler, Jörg, You, Wonsang   +4 more
core   +5 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Stress Impact on Resting State Brain Networks. [PDF]

PLoS ONE, 2013
Resting state brain networks (RSNs) are spatially distributed large-scale networks, evidenced by resting state functional magnetic resonance imaging (fMRI) studies. Importantly, RSNs are implicated in several relevant brain functions and present abnormal
José Miguel Soares, Adriana Sampaio, Luís Miguel Ferreira, Nadine Correia Santos, Paulo Marques, Fernanda Marques, Joana Almeida Palha, João José Cerqueira, Nuno Sousa   +8 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Automatic selection of resting-state networks with functional magnetic resonance imaging

Frontiers in Neuroscience, 2013
Functional magnetic resonance imaging (fMRI) during a resting-state condition can reveal the co-activation of specific brain regions in distributed networks, called resting-state networks, which are selected by independent component analysis (ICA) of the
Silvia Francesca eStorti, Emanuela eFormaggio, Roberta eNordio, Paolo eManganotti, Paolo eManganotti, Antonio eFiaschi, Antonio eFiaschi, Alessandra eBertoldo, Gianna Maria eToffolo   +8 more
doaj   +1 more source

The frequency gradient of human resting-state brain oscillations follows cortical hierarchies

bioRxiv, 2019
The human cortex is characterized by local morphological features such as cortical thickness, myelin content and gene expression that change along the posterior-anterior axis.
K. Mahjoory, J. Schoffelen, A. Keitel, J. Gross   +3 more
semanticscholar   +1 more source