Results 201 to 210 of about 17,412,001 (255)

Muscarinic agonists for schizophrenia: Bridging preclinical evidence and clinical enthusiasm

British Journal of Pharmacology, Volume 183, Issue 19, Page 5701-5731, October 2026.
Abstract Antipsychotic drugs targeting dopamine receptors have been used to treat schizophrenia for decades, primarily alleviating positive symptoms such as hallucinations and delusions. However, they provide limited benefit for cognitive and negative symptoms—major contributors to poor outcomes—and are frequently associated with significant side ...
Brian J. Morris, Judith A. Pratt
wiley   +1 more source

Slow-4 cerebellar activity tracks MMSE language-related task performance across the Alzheimer's disease spectrum: a multi-metric resting-state fMRI study. [PDF]

Front Neurosci
Mao H, Fu B, Song J, Jia X, Cheng L, Xiao H, Zhang L.   +6 more
europepmc   +1 more source

What makes a lonely child: environmental, health, and multimodal neuroimaging correlates of prospective loneliness in the ABCD study

Journal of Child Psychology and Psychiatry, Volume 67, Issue 10, Page 1714-1728, October 2026.
Background Loneliness in childhood is a growing public health concern, yet early multilevel candidate risk and protective factors remain insufficiently mapped. Systematic investigation is essential to guide prevention and intervention during sensitive developmental periods.
Ting Yat Wong, Ting Sam Wong, Wai Kai Hou, Angel Nga Man Leung, Jie Xiao, Kenneth S. L. Yuen, Simon S. Y. Lui, Anqi Qiu, Tyler M. Moore, Ruben C. Gur   +9 more
wiley   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, Volume 13, Issue 9, Page 1919-1929, September 2026.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Spatial and temporal connectivity of brain resting-state fMRI during music-induced analgesia in fibromyalgia patients. [PDF]

Front Hum Neurosci
Hou J, Liu Y, Hosseini T, Zheng M, Liu X, Sun C.   +5 more
europepmc   +1 more source

Mechanism‐Driven Nanoformulations for Cognitive Impairment Induced by Intermittent Hypoxia and Periodontitis

Advanced Materials, Volume 38, Issue 49, 1 September 2026.
Clinically, intermittent hypoxia (IH) is often accompanied by periodontitis, which accelerates cognitive impairment induced by IH. Novel Janus mesoporous gold‐silica nanoformulations (RVG‐Au&mSiO2‐TPP‐VB) enable intranasal delivery, achieve hierarchical targeting to neuronal mitochondria, effectively scavenge reactive oxygen species, inhibit the HIF‐1α/
Kai‐Run Zhang, Tianbao Zhu, An‐Qi Liu, Jia‐Jia Deng, Ya‐Li Han, Sheng‐Cai Qi, Xue Liu, Tian‐Yi Jiang, Ming‐Rui Zhai, Yu‐Ying He, Xiu‐Juan Li, Hong‐Ting Da, Rui Xu, Xiaomin Li, Jun Gao, Yue‐Hua Liu   +15 more
wiley   +1 more source

Targeted Vestibular Rehabilitation Accelerates Symptom Relief by Promoting Vestibular Compensation in BPPV Patients With Residual Symptoms: Evidence From Resting-State fMRI. [PDF]

Brain Behav
Yin G, Liang Y, Huang Q, Li L, Lin J, Liu C, Li Z, Zeng X.   +7 more
europepmc   +1 more source

Personalized Network‐Guided Neuromodulation Enhances Human Working Memory

Advanced Science, Volume 13, Issue 49, 3 September 2026.
A personalized neuromodulation framework combining individualized functional brain network targeting with real‐time neural decoding is introduced. Using concurrent TMS–fMRI, participant‐specific stimulation targets and optimal frequencies are identified. Only optimal‐frequency stimulation improves working memory across sessions.
Ahsan Khan, Hongming Li, Camille Blaine, Julie Grier, Ethan Hammett, Almaris Figueroa‐Gonzalez, Sarai Garcia, Romain Duprat, Justin Reber, Joseph Deluisi, Christos Davatzikos, Theodore D. Satterthwaite, Yong Fan, Desmond J. Oathes   +13 more
wiley   +1 more source

DMN function changes on resting state fMRI in perimenopausal women. [PDF]

Open Med (Wars)
Liu N, Zhang Y, Fu W, Liu H.
europepmc   +1 more source

Parcellation of functional subregions using an improved affinity propagation clustering algorithm based on structure‐function coupling

General Psychiatry, Volume 39, Issue 5, October 2026.
Yanling Li, Junbiao He, Shen'ao Li, Hongtao Yi, Fengmei Lu, Jingjing Gao   +5 more
wiley   +1 more source