Results 221 to 230 of about 18,088,910 (254)

The underlying neurobiology of social isolation and loneliness in middle‐older adults: A systematic review

open access: yesAlzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract Social isolation and loneliness are distinct but overlapping dementia risk factors, though their underlying neurobiological mechanisms remain unclear. A systematic search identified 42 studies examining social isolation, loneliness, and neurobiological outcomes in middle‐aged and older adults, including structural and functional neuroimaging ...
Jade Guarnera   +5 more
wiley   +1 more source

EEG‐based brain effective and functional connectivity predict PET‐defined amyloid positivity in cognitively normal individuals

open access: yesAlzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION Early identification of amyloid‐beta (Aβ) pathology is essential for timely intervention in Alzheimer's disease (AD), as Aβ accumulation precedes clinical symptoms by years. METHODS We predicted positron emission tomography (PET) ‐defined Aβ status in cognitively normal individuals using non‐invasive resting‐state dry ...
Boxin Sun   +12 more
wiley   +1 more source

APOE ε4 gene dose drives a canonical and predictable topography of amyloid deposition

open access: yesAlzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION Apolipoprotein E ε4 (APOE ε4) carriership is associated with higher amyloid burden in Alzheimer's disease (AD), but whether it constrains the spatial predictability of amyloid deposition at the individual level remains unknown.
Augusto J. Mendes   +8 more
wiley   +1 more source

Atypical Cerebellar Responses are Associated with Altered Neural Habituation during Sensory Stimulation in Autism

open access: yesAutism Research, Volume 19, Issue 10, October 2026.
ABSTRACT Sensory processing atypicalities are highly prevalent in autistic youth; yet, the neural mechanisms underlying these differences are not well understood. While the cerebellum plays a key role in sensorimotor coordination and is structurally and functionally atypical in the autistic brain, it has been overlooked in research investigating ...
Melis E. Cakar   +4 more
wiley   +1 more source

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