Results 71 to 80 of about 175,351 (257)

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

Thermoregulatory and cardiovascular responses to creatine, glycerol and alpha lipoic acid in trained cyclists [PDF]

, 2012
Background It has been shown that supplementation with creatine (Cr) and glycerol (Gly), when combined with glucose (Glu) necessary for the enhancement of Cr uptake by skeletal muscle, induces significant improvements in thermoregulatory and ...
Hambly, C., Lee, W.C., Malkova, D., Pantazis, T., Pitsiladis, Y.P., Polyviou, T.P., Speakman, J.R.   +6 more
core   +2 more sources

P5621Diagnostic accuracy of resting full-cycle ratio in the non-culprit artery of acute patients

European Heart Journal, 2019
Abstract Introduction Resting full-cycle ratio (RFR) is a novel non-hyperemic index of coronary stenosis severity, independent of the timing within the cardiac cycle. Recent data has demonstrated good correlation between RFR and Fractional Flow Reserve (FFR) in stable coronary disease (SCD).
M A Tamargo Delpon, E Gutierrez, F Diez-Delhoyo, H Gonzalez-Saldivar, A R Rivera, A Casado, M E Vazquez, R Sanz, J Soriano, J Elizaga, F J Fernandez-Aviles   +10 more
openaire   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Impact of Kidney Function on Physiological Assessment of Coronary Circulation

Reviews in Cardiovascular Medicine
Background: Diagnosing myocardial ischemia in chronic kidney disease (CKD) patients is crucial since coronary artery disease (CAD) forms the predominant cause of mortality in these patients.
Wojciech Zasada, Barbara Zdzierak, Tomasz Rakowski, Beata Bobrowska, Agata Krawczyk-Ożóg, Sławomir Surowiec, Stanisław Bartuś, Andrzej Surdacki, Artur Dziewierz   +8 more
doaj   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Diabetes-Related Differences in the Predictive Value of the Physiological Assessment of Myocardial Ischemia for Long-Term Clinical Outcomes

Diabetology
Background/Objectives: Physiological assessment of borderline coronary lesions is recommended by current guidelines for revascularization decision-making.
Wojciech Zasada, Beata Bobrowska, Agata Krawczyk-Ożóg, Tomasz Rakowski, Stanisław Bartuś, Artur Dziewierz, Barbara Zdzierak   +6 more
doaj   +1 more source

Biopsychosocial determinants of hand function and its trajectories over five years in patients with hand osteoarthritis

Arthritis Care &Research, Accepted Article.
Objectives This study aimed to investigate hand function trajectories over 5 years in primary hand osteoarthritis. Additionally, determinants of baseline and longitudinal hand function were assessed. Methods 538 patients with both baseline and 5‐year study visits were analyzed.
Annemiek V.E.M. Olde Meule, Coen van der Meulen, Jos Runhaar, Frits R. Rosendaal, Margreet Kloppenburg   +4 more
wiley   +1 more source

Reproductive biology of blue marlin (Makaira nigricans) in the western Pacific Ocean [PDF]

, 2009
The reproductive biology of blue marlin (Makaira nigricans) was assessed from 1001 fish (ranging from 121 to 275 cm in eye-to-fork length; EFL) caught by Taiwanese offshore longliners in the western Pacific Ocean from September 2000 to December ...
Chien-Chung Tszeng, Chien-Chung Tszeng, Su-Zan Yeh, Su-Zan Yeh, Sun, Chi-Lu, Yi-Jay Chang, Yi-Jay Chang   +3 more
core  

6115Influence of microvascular function and coronary flow in the diagnostic precision of resting full-cycle ratio

European Heart Journal, 2019
Abstract Introduction Resting full-cycle ratio (RFR) has been recently described as a non-hyperemic index of coronary stenosis with good concordance with Fractional Flow Reserve (FFR). However, there is no information concerning the influence of microvascular function and coronary flow on RFR results.
M A Tamargo Delpon, E Gutierrez Ibanes, F Diez-Delhoyo, H Gonzalez-Saldivar, A R Rivera, A Casado, M E Vazquez, R Sanz, J Soriano, J Elizaga, F J Fernandez-Aviles   +10 more
openaire   +1 more source