Results 41 to 50 of about 6,689,988 (287)

The scaling of human basal and resting metabolic rates

European Journal of Applied Physiology, 2020
In tachymetabolic species, metabolic rate increases disproportionately with body mass, and that inter-specific relationship is typically modelled allometrically. However, intra-specific analyses are less common, particularly for healthy humans, so the possibility that human metabolism would also scale allometrically was investigated.Basal metabolic ...
Heather M. Bowes, Catriona A. Burdon, Nigel A. S. Taylor   +2 more
openaire   +4 more sources

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Thyroid hormones correlate with resting metabolic rate, not daily energy expenditure, in two charadriiform seabirds

Biology Open, 2013
Summary Thyroid hormones affect in vitro metabolic intensity, increase basal metabolic rate (BMR) in the lab, and are sometimes correlated with basal and/or resting metabolic rate (RMR) in a field environment.
Kyle H. Elliott, Jorg Welcker, Anthony J. Gaston, Scott A. Hatch, Vince Palace, James F. Hare, John R. Speakman, W. Gary Anderson   +7 more
doaj   +1 more source

ATP consumption by sarcoplasmic reticulum Ca²⁺ pumps accounts for 40-50% of resting metabolic rate in mouse fast and slow twitch skeletal muscle. [PDF]

PLoS ONE, 2013
The main purpose of this study was to directly quantify the relative contribution of Ca²⁺ cycling to resting metabolic rate in mouse fast (extensor digitorum longus, EDL) and slow (soleus) twitch skeletal muscle.
Ian Curtis Smith, Eric Bombardier, Chris Vigna, A Russell Tupling   +3 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Resting Metabolic Rate and Respiratory Quotient in Human Longevity [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2005
Significant changes in body composition, body fat distribution, and resting metabolic rate (RMR) occur with aging. Interestingly, studies on human longevity pointed out that long-lived subjects are less prone to the anthropometrics and metabolic derangement normally observed in the elderly.
RIZZO, Maria Rosaria, MARI D, BARBIERI, Michelangela, RAGNO E, GRELLA R, PROVENZANO R, VILLA I, ESPOSITO, Katherine, GIUGLIANO, Dario, PAOLISSO, Giuseppe   +9 more
openaire   +3 more sources

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

Revisiting the calculation of PAL from physical activity data

BMJ Open Sport & Exercise Medicine
The physical activity level (PAL), defined as the ratio of total daily energy expenditure to resting metabolic rate, is widely used to assess energy requirements in both clinical and research settings. PAL is often not estimated directly—via measurements
Faidon Magkos
doaj   +1 more source

Field energetics and lung function in wild bottlenose dolphins, Tursiops truncatus, in Sarasota Bay Florida [PDF]

Royal Society Open Science, 2018
We measured respiratory flow rates, and expired O2 in 32 (2–34 years, body mass [Mb] range: 73–291 kg) common bottlenose dolphins (Tursiops truncatus) during voluntary breaths on land or in water (between 2014 and 2017). The data were used to measure the
A. Fahlman, M. Brodsky, R. Wells, K. McHugh, J. Allen, A. Barleycorn, J. C. Sweeney, D. Fauquier, M. Moore   +8 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source