Results 201 to 210 of about 1,109,777 (250)

H4K12 Lactylation Impairs Dopaminergic Neuron Energy Metabolism via the HIF‐1α/NDUFS1 Pathway in Parkinson's Disease

Advanced Science, EarlyView.
Lactate and H4K12la are elevated in Parkinson's disease. Mechanistically, p300‐mediated H4K12la enrichment at the HIF‐1α promoter upregulates HIF‐1α, which represses Ndufs1, impairing mitochondrial respiration and energy homeostasis in DA neurons.
Yingyao Liu, Xi Li, Wenxuan He, Fenglin Li, Qican Ou, Yao Liu, Jiang Lei, Yanzi Bao, Huaxin Huang, Wei Feng, Yuanguang Tang, Xiaohui Qiu, Lu Gan, Yuefei Shen, Jin Wang, Yousheng Xiao   +15 more
wiley   +1 more source

PDHA1 Hyperactivation‐Mediated Glucose Metabolism Reprogramming Fuels Neutrophil NETosis and Promotes Acute Lung Injury

Advanced Science, EarlyView.
During NETosis, neutrophils shift metabolically toward enhanced OXPHOS and partially reduced glycolysis. This shift is driven by PDHA1 hyperactivity‐dependent selective metabolic reprogramming. The neutrophil‐targeted nanoparticle 3‑FP‑BSA NPs effectively inhibit NETosis and attenuate ALI.
Yu‐Biao Liu, Wen‐Jing Zhong, Chen‐Yu Zhang, Meng‐Rui Chen, Nan‐Shi‐Yu Yang, Han‐Xi Sha, Yan‐Ling Qiu, Hui Chen, Jin‐Tong Yang, Li‐Ying Liang, Jian‐Bing Xiong, Shao‐Kun Liu, Cha‐Xiang Guan, Jia‐Xi Duan, Yong Zhou   +14 more
wiley   +1 more source

Resting metabolism of mouse papillary muscle

Pflügers Archiv - European Journal of Physiology, 2005
The aims of this study were to measure the resting metabolic rate of isolated mouse papillary muscles and to determine whether diffusive O2 supply is adequate to support the resting metabolism. Resting metabolism of left ventricular papillary muscles was measured in vitro (27 degrees C) using the myothermic technique.
Widen, Cecilia, Barclay, Chris
openaire   +5 more sources

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Increased Resting Metabolism in Neurofibromatosis Type 1

Clinical Nutrition ESPEN, 2019
Neurofibromatosis type 1 (NF1) is an autosomal dominant genetic disease that is characterized by neurocutaneous changes with multisystem involvement. A previous study with adults with NF1 revealed that changes in total energy expenditure were related to food consumption and body composition.
Nilton Alves de Rezende, Adriana Maria Kakehasi, Ann Kristine Jansen   +2 more
exaly   +3 more sources

Resting Metabolism and Heat Increment of Feeding in Mandarin Fish (Siniperca chuatsi) and Chinese Snakehead (Channa argus)

Comparative Biochemistry and Physiology Part A, Molecular & Integrative Physiology, 2000
Resting metabolism was measured in immature mandarin fish Siniperca chuatsi weighing 42.1-510.2 g and Chinese snakehead Channa argus weighing 41.5-510.3 g at 10, 15, 20, 25, 30 and 35 degreesC.
Jiashou Liu, Yibo Cui, Jiankang Liu
exaly   +1 more source

Familial Dependence of the Resting Metabolic Rate

New England Journal of Medicine, 1986
Human obesity is known to be a familial disorder. We studied 130 nondiabetic adult southwestern American Indians (74 men and 56 women) from 54 families to determine whether the resting metabolic rate, as measured by indirect calorimetry, is a familial trait that is independent of individual differences in fat-free mass (estimated mass of metabolically ...
Bogardus, C, Lillioja, S, Ravussin, E, Abbott, W, Zawadzki, J K, Young, A, Knowler, W C, Jacobowitz, R, Moll, P   +8 more
openaire   +4 more sources

Resting Metabolic Rate of Elderly Vietnamese

Annals of Nutrition and Metabolism, 2007
<i>Background/Aims:</i> To evaluate the FAO/WHO/UNU equations for predicting resting metabolic rate (RMR) in elderly Vietnamese. <i>Methods:</i> A cross-sectional study involving healthy and elderly subjects was carried out at the Basic Nutrition Department, National Institute of Nutrition, Vietnam.
Bui Thi, Nhung, Nguyen Cong, Khan, Le Thi, Hop, Nguyen Thi, Lam, Nguyen Le Bao, Khanh, Do Thi Kim, Lien, Masayo, Nakamori, Vu Thi Thu, Hien, Afework, Kassu, Shigeru, Yamamoto   +9 more
openaire   +2 more sources

Resting metabolic rate in obesity

Postgraduate Medical Journal
Abstract The prevalence of obesity has continued to rise, and obesity and its attendant metabolic disorders are major global health threat factors. Among the current interventions for obesity, none have demonstrated sustained efficacy in achieving long-term outcomes.
LingHong, Huang, ZhiFeng, Guo, ZhengRong, Jiang, YaJing, Xu, HuiBin, Huang   +4 more
openaire   +2 more sources

Resting Metabolic Rate: Measurement Reliability

Journal of Parenteral and Enteral Nutrition, 1987
Resting metabolic rate (RMR) usually is measured by indirect calorimetry for a brief interval, and the results are then extrapolated to 24‐hr resting energy production. The aim of the current study was to examine the validity of this approach by measuring the within‐ and between‐day variability in RMR.
M L, Leff, J O, Hill, A A, Yates, G A, Cotsonis, S B, Heymsfield   +4 more
openaire   +2 more sources

Allometry of resting metabolic rate in cockroaches

Comparative Biochemistry and Physiology Part A: Physiology, 1989
1. Resting VO2 at 22.7 degrees C was 0.217 +/- 0.007 ml O2/g/hr in Nauphoeta cinerea of 0.51 +/- 0.008 g body mass. 2. Whole animal resting metabolic rate for 11 cockroach species scaled allometrically: VO2 = 0.261 M0.776. 3. Allometry of resting VO2 among cockroach species is similar to that in vertebrates, and is consistent with models based on both "
Coelho, J. R., Moore, A. J.
openaire   +3 more sources