Results 121 to 130 of about 11,023,971 (404)

The Effect of Aging on Resting State Connectivity of Predefined Networks in the Brain

open access: yesFrontiers in Aging Neuroscience, 2019
Recent studies have found a deleterious effect of age on a wide variety of measures of functional connectivity, and some hints at a relationship between connectivity at rest and cognitive functioning.
Eleanna Varangis   +3 more
semanticscholar   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Rest and activity states in a gray whale

open access: yesJournal of Sleep Research, 2000
The behaviour of a female gray whale (Eschrichtius robustus) that had been rescued 14 months previously was recorded continuously on a video‐recorder for 9 days at ‘Sea World’ in San Diego. On average, during the first six recording days, active wakefulness accounted for 37.9 ± 1.7% of each 24 h; transitional stage for 17.4 ± 1.4% and rest for 41.2 ± 1.
O I, Lyamin   +4 more
openaire   +3 more sources

Resting-state functional connectivity alterations after mild COVID-19 infection

open access: yesBMC Infectious Diseases
The long-term effects of coronavirus disease 2019 (COVID-19) are more pronounced after severe infection, although years after the pandemic was declared, long-term neurological complications after mild infection have begun to unfold.
Anna Szente   +12 more
doaj   +1 more source

Resting-state and vocabulary tasks distinctively inform on age-related differences in the functional brain connectome

open access: yes, 2019
Most of the current knowledge about age-related differences in brain neurofunctional organisation stems from neuroimaging studies using either a “resting state” paradigm, or cognitive tasks for which performance decreases with age. However, it remains to
Jason Steffener   +17 more
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Task vs. Rest - Different Network Configurations between the Coactivation and the Resting-State Brain Networks

open access: yesFrontiers in Human Neuroscience, 2013
There is a growing interest in studies of human brain networks using resting-state functional magnetic resonance imaging (fMRI). However, it is unclear whether and how brain networks measured during the resting-state exhibit comparable properties to ...
Xin eDi   +3 more
doaj   +1 more source

Resting - State EEG Indicates Unstable Microstates in Visual Snow Syndrome [PDF]

open access: yes, 2023
Background: EEG microstates account for a significant amount of the variance in resting-state EEG activity and are considered the basic building blocks of human neurological processes.
Schankin, Christoph   +3 more
core  

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