Results 121 to 130 of about 17,612,945 (252)

Comparison of performance between task-fMRI and resting state fMRI.

open access: yes, 2018
Comparison of performance between task-fMRI and resting state fMRI.
Michelle Miller-Thomas (5440193)   +14 more
core   +1 more source

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux   +26 more
wiley   +1 more source

Disentangling the effect of brain insulin resistance on brain health (BIR‐BrainHealth): Rationale and study protocol

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims Insulin signalling in the brain is crucial for systemic metabolic regulation and cognitive function. In some individuals, these effects are reduced, a phenomenon referred to as brain insulin resistance (BIR). This condition may contribute to the elevated risk of cognitive decline and dementia in diabetes, yet its prevalence, mechanisms ...
Sabrina Wangler   +11 more
wiley   +1 more source

Energetic dysregulations in psychotic disorders: Targets for new therapeutics

open access: yesThe FEBS Journal, EarlyView.
The present review synthesizes literature documenting aberrant energy production and use, specifically related to mitochondrial and redox dysregulation, in psychotic disorders. Findings from different levels of investigation—genetic, cellular, and in vivo imaging—converge on aberrant energy metabolism as a hallmark of psychotic disorders.
Jacey Anderson   +10 more
wiley   +1 more source

Decreased interhemispheric coordination in schizophrenia: A resting state fMRI study

open access: yes, 2012
Schizophrenia has been increasingly conceptualized as a disorder of brain connectivity, in large part due to findings emerging from white matter and functional connectivity (FC) studies. This work has focused primarily on within-hemispheric connectivity,
Butler, Pamela D.   +7 more
core   +1 more source

Annual Research Review: Psychosis in children and adolescents: key updates from the past 2 decades on psychotic disorders, psychotic experiences, and psychosis risk

open access: yesJournal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 460-476, April 2025.
Psychosis in children and adolescents has been studied on a spectrum from (common) psychotic experiences to (rare) early‐onset schizophrenia spectrum disorders. This research review looks at the state‐of‐the‐art for research across the psychosis spectrum, from evidence on psychotic experiences in community and clinical samples of children and ...
Ian Kelleher
wiley   +1 more source

Resting state fMRI and electrophysiology in rats

open access: yes
<p>The dataset includes electrophysiology and whole-brain resting-state fMRI simultaneously recorded from adult male Long-Evans rats. Invasive electrophysiology was concurrently recorded from two brain regions: the anterior cingulate cortex (ACC ...
Tu, Wenyu, Cramer, Samuel, Zhang, Nanyin
core   +1 more source

Annual Research Review: What processes are dysregulated among emotionally dysregulated youth? – a systematic review

open access: yesJournal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 516-546, April 2025.
Proliferation of the term “emotion dysregulation” in child psychopathology parallels the growing interest in processes that influence negative emotional reactivity. While it commonly refers to a clinical phenotype where intense anger leads to behavioral dyscontrol, the term implies etiology because anything that is dysregulated requires an impaired ...
Joseph C. Blader   +2 more
wiley   +1 more source

Research Review: A scoping review exploring the needs, barriers, and facilitators to the collection of biological data in adolescence for mental health research

open access: yesJournal of Child Psychology and Psychiatry, EarlyView.
Background There is increasing recognition of the challenge of representativeness in data, including economic, social, and ethnic diversity, in biological mental health research. This is a particular challenge in adolescence, where brain and body development are impacted by the environment.
Courtney Worrell   +29 more
wiley   +1 more source

Task-based functional connectivity is sufficient to capture individual differences in functional selectivity across multiple cortical systems

open access: yesNeuroImage
Most studies of brain networks use resting-state fMRI to characterize the brain’s intrinsic functional organization. However, recent work has questioned whether we should rely exclusively on resting-state data to define this organization.
Isaac Liao   +4 more
doaj   +1 more source

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