Results 81 to 90 of about 101,028 (286)

Resting state cortical EEG rhythms in Alzheimer's disease: toward EEG markers for clinical applications: a review [PDF]

, 2012
The human brain contains an intricate network of about 100 billion neurons. Aging of the brain is characterized by a combination of synaptic pruning, loss of cortico-cortical connections, and neuronal apoptosis that provoke an age-dependent decline of ...
Lizio, Roberta, De Vico Fallani, Fabrizio, Fabrizio Vecchio, F. De Vico Fallani, Frisoni, Giovanni, Fabrizio De Vico Fallani, Giulio Verrienti, Giovanni Frisoni, Vecchio, Fabrizio, Rossini, Paolo M, G. Verrienti, P. M. Rossini, F. Vecchio, Verrienti, Giulio, Frisoni, Giovanni B., Paolo M. Rossini, Rossini, Paolo M., Babiloni, Claudio, Fde V. Fallani, Blinowska, Katarzyna, G. Frisoni, Rossini, Paolo Maria, Claudio Babiloni, K. Blinowska, Katarzyna Blinowska, Roberta Lizio   +25 more
core   +1 more source

Effects of Systemic Physiology on Mapping Resting-State Networks Using Functional Near-Infrared Spectroscopy

Frontiers in Neuroscience, 2022
Resting-state functional connectivity (rsFC) has gained popularity mainly due to its simplicity and potential for providing insights into various brain disorders.
Androu Abdalmalak, Androu Abdalmalak, Sergio L. Novi, Karnig Kazazian, Loretta Norton, Tatiana Benaglia, Marat Slessarev, Derek B. Debicki, Derek B. Debicki, Keith St. Lawrence, Rickson C. Mesquita, Adrian M. Owen, Adrian M. Owen, Adrian M. Owen   +13 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Variability in resting-state brain networks

, 2020
Recently, new studies have detected that group average brain networks display distinct organization compared with individual subject networks. In particular, each subject network presents a distinctive topology.
Oliver i Alabau, Isaura
core   +1 more source

Shifted Coupling of EEG Driving Frequencies and fMRI Resting State Networks in Schizophrenia Spectrum Disorders [PDF]

, 2013
INTRODUCTION: The cerebral resting state in schizophrenia is altered, as has been demonstrated separately by electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) resting state networks (RSNs).
Jann, Kay, Martinus Hauf (467004), Hauf, Martinus, Kay Jann, Thomas Dierks, Kay Jann (361636), Nadja Razavi, Mara Kottlow, Razavi, Nadja, Koenig, Thomas, Kottlow, Mara, Martinus Hauf, Dierks, Thomas, Thomas Koenig (153106), Werner Strik (109393), Thomas Dierks (109391), Thomas Koenig, Werner Strik, Mara Kottlow (361637), Nadja Razavi (456730), Strik, Werner   +20 more
core   +1 more source

Dynamic recruitment of resting state sub-networks [PDF]

NeuroImage, 2015
Resting state networks (RSNs) are of fundamental importance in human systems neuroscience with evidence suggesting that they are integral to healthy brain function and perturbed in pathology. Despite rapid progress in this area, the temporal dynamics governing the functional connectivities that underlie RSN structure remain poorly understood.
George C. O'Neill, Markus Bauer 0003, Mark W. Woolrich, Peter G. Morris, Gareth R. Barnes, Matthew J. Brookes   +5 more
openaire   +2 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Resting-state network organisation in children with traumatic brain injury

, 2023
Children with traumatic brain injury are at risk of neurocognitive and behavioural impairment. Although there is evidence for abnormal brain activity in resting-state networks after TBI, the role of resting-state network organisation in paediatric TBI ...
C C Kooper (13309017), P J W Pouwels (13309020), M Königs (13309032), Edith Botchway (13068198), M Engelen (13309026), J Oosterlaan (13309029), H Bruining (13309023)   +6 more
core  

The Impact of Normalization and Segmentation on Resting-State Brain Networks [PDF]

Brain Connectivity, 2015
Graph theory has recently received a lot of attention from the neuroscience community as a method to represent and characterize brain networks. Still, there is a lack of a gold standard for the methods that should be employed for the preprocessing of the data and the construction of the networks, as well as a lack of knowledge on how different ...
Ricardo Magalhães, Paulo Marques 0001, José Miguel Soares, Victor Alves, Nuno J. Sousa   +4 more
openaire   +3 more sources