Results 111 to 120 of about 21,924 (247)

Update on Medical Treatments for Essential Tremor: An International Parkinson and Movement Disorder Society Evidence‐Based Medicine Review

Movement Disorders, Volume 41, Issue 4, Page 815-825, April 2026.
Abstract Background The first International Parkinson and Movement Disorder Society Evidence‐Based Medicine (MDS‐EBM) review for essential tremor (ET) was published in 2019; since then, the modified Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology was adopted by MDS, and new evidence exists.
Deepa Dash, Verónica Bruno, Petra Schwingenschuh, Kelly E. Lyons, Eng‐King Tan, Claudia M. Testa, Santiago Perez Lloret, Bettina Balint, João Costa, Rob M.A. de Bie, Monty A. Silverdale, Ai Huey Tan, Tiago A. Mestre   +12 more
wiley   +1 more source

When Pathways Converge: Iron, Lipid Peroxidation, and α‐Synuclein in Ferroptosis‐Driven Dopaminergic Neurodegeneration

Journal of Neurochemistry, Volume 170, Issue 4, April 2026.
Dopaminergic neurons are particularly susceptible to ferroptosis. Pacemaking activity–driven calcium (Ca2+) influx increases metabolic demand and reactive oxygen species (ROS) production, promoting iron release from aconitase. Alpha‐synuclein (α‐syn) enhances iron uptake via transferrin receptor 1 (TfR1) and exhibits ferrireductase activity, converting
Carmem L. Sperlich, Brent R. Stockwell, Marcelo Farina   +2 more
wiley   +1 more source

The treatment of restless legs syndrome and periodic limb movement disorder: a plain language summary of the American Academy of Sleep Medicine Clinical Practice Guidelines [PDF]

Brian B. Koo, Joseph Andrew Berkowski, Mark J. Buchfuhrer   +2 more
openalex   +1 more source

The Effects of Daridorexant on Patients With Comorbid Insomnia Disorder and Untreated Mild Obstructive Sleep Apnoea: A Post Hoc Subgroup Analysis of a Phase 3, Randomised Clinical Trial

Journal of Sleep Research, Volume 35, Issue 2, April 2026.
ABSTRACT Daridorexant, a dual orexin receptor antagonist, is approved for the treatment of insomnia disorder in adults. Approximately 30%–35% of patients with insomnia disorder also have obstructive sleep apnoea (OSA) of any severity. It is unclear whether sleep medications provide safe and effective treatment for insomnia in these patients.
Christopher J. Lettieri, Orestis Briasoulis, Damien Léger, Pierre‐Philippe Luyet, Jean‐Louis Pépin, Stuart F. Quan, Janna Raphelson, Paul Saskin, Atul Malhotra   +8 more
wiley   +1 more source

Management of Insomnia Complaints by Non‐Sleep Specialist Physicians: A French DELPHI Consensus

Journal of Sleep Research, Volume 35, Issue 2, April 2026.
ABSTRACT Insomnia is the most prevalent sleep disorder and a major public health concern, affecting chronically up to 19% of the adult population in France. Despite its significant impact on quality of life, mental health, and cardiometabolic disease, insomnia disorder remains underdiagnosed and inadequately managed.
Pierre‐Alexis Geoffroy, Jean‐Louis Pépin, Marjorie Guillet, Jean‐Bastien Micoulaud‐Franchi, Yves Dauvilliers, Damien Léger, Sylvie Royant‐Parola   +6 more
wiley   +1 more source

PNL13 PROFILE OF PATIENTS SUFFERING FROM RESTLESS LEGS SYNDROME AND ESTIMATION OF THEIR ANNUAL COST IN AN AMBULATORY CARE SETTING, IN FRANCE

, 2004
F. Maurel, Benjamin Girard, Anne Crochard, M Henri, Abdelkader El Hasnaoui, C Le Pen   +5 more
openalex   +1 more source

Patterns of gray matter alterations in migraine and restless legs syndrome [PDF]

, 2018
Fu‐Chi Yang, Kun‐Hsien Chou, Pei‐Lin Lee, Jiu‐Haw Yin, Shao‐Yuan Chen, Hung‐Wen Kao, Yueh‐Feng Sung, Chung‐Hsing Chou, Chia‐Kuang Tsai, Chia‐Lin Tsai, Ching‐Po Lin, Jiunn‐Tay Lee   +11 more
openalex   +1 more source

Sleep in Functional Motor Disorders: A Case–Control Polysomnographic Study

Journal of Sleep Research, Volume 35, Issue 2, April 2026.
ABSTRACT Sleep problems are frequent in functional motor disorders (FMDs). Surprisingly, objective correlates of impaired sleep and its relationship to other comorbidities have been understudied, and no polysomnographic study is available. We aimed to map the polysomnographic parameters in the context of self‐reported sleep and mood symptoms and search
Jiří Nepožitek, Simona Dostálová, Martin Jirásek, Gabriela Chaloupková, Zuzana Forejtová, Lucia Nováková, Veronika Rottová, Veronika Konvičná, Karel Šonka, Mark J. Edwards, Tereza Serranová   +10 more
wiley   +1 more source

Sleep and Rhythmic Profile After Pineal Gland Removal in Humans

Journal of Sleep Research, Volume 35, Issue 2, April 2026.
ABSTRACT Melatonin, a hormone produced by the pineal gland, is classically described as a central circadian modulator. However, the impact of its absence on circadian rhythmicity in humans remains poorly understood. Pinealectomised patients, in whom melatonin secretion is chronically suppressed, represent a valuable clinical model to investigate the ...
Renata de Andrade Prado Gobetti, Clarissa Bueno, Letícia M. S. F. A. Soster, Anna Carolina de Campos de Barros Luvizotto Monazzi, Fernanda Gaspar do Amaral, Andréa Maria Capellano, Nasjla Saba da Silva, José Cipolla‐Neto   +7 more
wiley   +1 more source

The Effect of Selected Core Stability Exercises on Restless Legs Syndrome and Quality of Life in the Elderly Undergoing Hemodialysis

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2018
Background and Objectives: The elderly individuals undergoing hemodialysis have lower quality of life compared to their healthy counterparts due to the complications associated with treatment and sedentary lifestyle.
Mehrdad Bastani, Gholamali Ghasemi, Morteza sadeghi   +2 more
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