Results 131 to 140 of about 1,314,107 (247)

Parkinson's disease under dopamine replacement therapy as a human framework for studying addiction‐relevant mechanisms

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Addiction is a chronic relapsing condition characterized by compulsive reward seeking and impaired behavioral control, associated with major individual and societal burden. Mechanistic investigation in humans remains constrained by ethical limitations, uncontrolled exposure histories, and ecological confounds.
Vanessa Fleury   +6 more
wiley   +1 more source

Lifestyle modification in atrial fibrillation: Mechanisms, phenotypes and ablation outcomes

open access: yesExperimental Physiology, EarlyView.
Abstract Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia and is associated with significant morbidity, mortality and healthcare utilization. Catheter ablation is increasingly used as a rhythm‐control intervention for patients with symptomatic paroxysmal and persistent AF, yet recurrence rates remain suboptimal.
Konstantinos Grigoriou   +11 more
wiley   +1 more source

Prognostic value of restless legs syndrome in hemodialysis patients: a systematic review and meta-analysis

open access: yes, 2017
Jing Li,1,* Tao Zhang,2,* Qingmiao Shao3 1Department of Transplantation, The First Central Hospital of Tianjin, 2Department of Nephrology, The First Affiliated Hospital of Tianjin Chinese Medical University, 3Department of Cardiology, The Second ...
Li J, Zhang T, Shao Q
core  

Mianserin-Induced Restless Legs Syndrome

open access: yes, 1989
Restless legs syndrome was observed in three patients receiving mianserin. The symptoms resolved when the treatment was discontinued or reduced.
In-Ho Paik   +4 more
core   +1 more source

Involvement in daily life activities from the perspectives of children and young people with childhood‐onset disabilities: A scoping review

open access: yesDevelopmental Medicine &Child Neurology, Volume 68, Issue 10, Page 1351-1364, October 2026.
This scoping review aimed to understand the construct ‘involvement’ in daily life activities from the perspective of children and young people with childhood‐onset disabilities. We identified six conceptual ideas, including a continuum of inner dedication or investment in‐the‐moment, and five others reflecting how children and young people process ...
Vera C Kaelin   +4 more
wiley   +1 more source

The restless legs syndrome

open access: yes, 2001
The restless legs syndrome (RLS) is a common disease with a prevalence of 2-10 %. An imperative desire to move lower limbs because of paraesthesias, dysaesthesias, or pain is typical.
Eckardt, K. M., Trenkwalder, Claudia
core   +1 more source

Brain‐derived plasma p‐tau217 shows enhanced dynamic range for Alzheimer's disease neuropathological change

open access: yesAlzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION Plasma phosphorylated tau (p‐tau), particularly p‐tau217, is a highly specific biomarker of Alzheimer's disease (AD) pathology. However, plasma p‐tau217 can be elevated in rare non‐AD conditions. Brain‐derived (BD) p‐tau217 may reduce these off‐target effects, but its performance against neuropathology has not been evaluated ...
Marisa N. Denkinger   +15 more
wiley   +1 more source

The Mediating Effect of Physiological Health Fear Between Depressive Mood and Sleep Quality in Elderly Parkinson's Disease Patients

open access: yesBrain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Objective To investigate the relationship between depressive mood and sleep quality in elderly patients with Parkinson's disease (PD), and to analyze the mediating role of fear of progression (FoP). Methods Between June 2024 and April 2025, 234 elderly patients with PD attending the Affiliated Hospital of Nantong University were enrolled ...
Ling Wu   +5 more
wiley   +1 more source

Therapeutic Potential of Oxiracetam in Neurocognitive Disorders: A Narrative Review

open access: yesBrain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Purpose: Cognitive impairment is a growing global health concern associated with aging, neurodegenerative diseases, stroke, and traumatic brain injury. Existing pharmacological treatments, including cholinesterase inhibitors and memantine, provide limited and variable benefits.
Hafsa Ali   +4 more
wiley   +1 more source

Sex and Gender Differences in Physical Activity, Sedentary Behavior, and Sleep During Traumatic Brain Injury Recovery: A Narrative Review

open access: yesEuropean Journal of Sport Science, Volume 26, Issue 9, September 2026.
ABSTRACT Traumatic brain injury (TBI) is a complex neurological condition with enduring consequences that extend well beyond the initial insult. Once regarded primarily as an acute event, TBI is now increasingly recognized as a chronic disorder associated with cognitive, emotional, and physical impairments.
Goretti España‐Irla   +5 more
wiley   +1 more source

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