Results 41 to 50 of about 19,620 (245)

Gabapentin Enacarbil: Pharmacotherapy of Restless Legs Syndrome

, 2010
Restless Legs Syndrome (RLS) is a prevalent sleep-associated movement disorder greatly affecting patients’ quality of life (QoL). Several drugs can be used to control this condition although the first-line dopamine agents often cause adverse effects. Non-
Ruth Jones, Andrea Eugenio Cavanna, Hugh Rickards, Jones, R, Rickards, Hugh, Cavanna, Andrea; id_orcid   +5 more
core   +1 more source

Restless Legs Syndrome in Patients with Epilepsy Under Levetiracetam Monotherapy [PDF]

, 2018
Objective: Restless Legs syndrome (RLS) is a frequent neurological disease. Levetiracetam (LEV) is an effective and broad-spectrum anticonvulsant drug. The aim of this study is to investigate the frequency of RLS in patients diagnosed with epilepsy who ...
Dilek Aslan Öztürk, Kutlu, Gülnihal, Genç, Fatma, Gülnihal Kutlu, Öztürk, Dilek Aslan, Abidin Erdal, Yasemin Ünal, Erdal, Abidin, Fatma Genç, Ünal, Yasemin, Yasemin Biçer Gömceli, Gömceli, Yasemin Biçer   +11 more
core   +1 more source

Cerebrospinal Fluid from Restless Legs Syndrome Patients Reduces Iron Uptake in Blood–Brain Barrier Endothelial Cells by Disrupting the Regulation of Transferrin Receptors

Annals of Neurology, EarlyView.
Model figure of BBBECs TfR1 regulation in control and RLS: Graphical representation of TfR1 regulation in ECs by IRPs and representing it can be dysregulated by miR‐124‐3p in ECs of RLS. FPN1, ferroportin; BBBEC, blood‐brain barrier endothelial cells; IRP, iron regulatory proytein1/2; TfR1, Transferrin receptor; IRE, Iron responsive elements; Tf ...
Kondaiah Palsa, Aurosman Pappus Sahu, David B. Rye, Lynn Marie Trotti, Irina A. Elcheva, Vladimir S. Spiegelman, James R. Connor   +6 more
wiley   +1 more source

Remission of severe restless legs syndrome and periodic limb movements in sleep after bilateral excision of multiple foot neuromas: a case report

Journal of Medical Case Reports, 2010
Introduction Restless legs syndrome is a sensorimotor neurological disorder characterized by an urge to move the legs in response to uncomfortable leg sensations.
Lettau Ludwig A, Gudas Charles J, Kaelin Thomas D   +2 more
doaj   +1 more source

HLA genotype testing for carbamazepine, oxcarbazepine and eslicarbazepine: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Carbamazepine is licensed in the United Kingdom for the treatment of epilepsy, bipolar disorder and trigeminal neuralgia. The related compounds oxcarbazepine and eslicarbazepine are licensed for the treatment of epilepsy. These drugs can cause immune‐mediated hypersensitivity reactions, which typically affect the skin, and can be of variable severity ...
Lucy Galloway, Cinzia Dello Russo, Nicholas Bass, Elvira Bramon, Helen Cross, Natalie Curley, Sarah Curran, Helen Davies, Jana De Villiers, William Evans, Bernhard Frank, Alice Groves, Judith Hayward, Jon Higham, Dyfrig A. Hughes, Shwe Sin Kyaw, Anthony G. Marson, Ailsa McLellan, Seth Mensah, Francis O'Neill, Jane Sargison, Sanjay M. Sisodiya, Jill Swan, Joanna M. Zakrewska, Munir Pirmohamed   +24 more
wiley   +1 more source

Are comorbid sleep disorders associated with higher risk for sudden unexpected death in epilepsy? Observations from a Canadian epilepsy clinic

Epilepsia, EarlyView.
Abstract Objective Pooled mortality is nearly three times higher in people with epilepsy (PWE). Approximately 80% of sudden unexpected death in epilepsy (SUDEP) events occur during sleep, and primary sleep disorders are prevalent in the general population and PWE.
Marion Lazaj, Ellen Lee, Tristan Derry, Helen Driver, Gavin P. Winston, Lysa Boissé Lomax, Ana Johnson, Garima Shukla   +7 more
wiley   +1 more source

Restless Legs Symptoms and Periodic Leg Movements in Sleep Among Patients with Parkinson’s Disease

Journal of Parkinson’s Disease, 2022
Background: The association between restless legs syndrome (RLS) and Parkinson’s disease (PD) remains controversial, with epidemiologic and descriptive evidence suggesting some potential overlap while mechanistic/genetic studies suggesting relative ...
Donald L. Bliwise, Elias G. Karroum, Sophia A. Greer, Stewart A. Factor, Lynn Marie Trotti   +4 more
doaj   +1 more source

Psychiatric Comorbidities in Restless Legs Syndrome

, 2016
Restless legs syndrome (RLS) is a neurological sleep disorder with frequent (39%) coexisting psychiatric comorbidities. Patients with any psychiatric comorbidity had fewer periodic leg movements in sleep.
Kallweit, Ulf, Bassetti, Claudio, Dahmen, Norbert, Seiz, Angela, Ehlert, Ulrike; https://orcid.org/, Werth, Esther, Bassetti, Claudio L A, Ehlert, Ulrike, Sefidan, Sandra, Manconi, Mauro, Werth, Esther; https://orcid.org/   +10 more
core   +1 more source

A Cross‐Sectional Survey Study Assessing the Quality of Life and Sleep in Spanish Psoriasis Patients

JEADV Clinical Practice, EarlyView.
Psoriasis impacts quality of life (QOL) and sleep (QOS), yet dermatology assessments often do not evaluate sleep. The Short‐form health survey (SF‐36) and Pittsburg sleep quality index (PSQI) further investigated patients’ QOL and QOS. Particularly women, unemployed patients, and those that use sleep medications had worse QOS and QOL.
Gabriela Piñero‐Crespo, María Isabel del Pino Rincón, Lilia Correa‐Selm, Raquel Hernández Sánchez, Amalia Pérez‐Gil   +4 more
wiley   +1 more source

Evaluating Sleep Apnea: In‐Lab Versus at‐Home Recording Time and the Impact of Positional Disease

The Laryngoscope, EarlyView.
We evaluated the minimum recording time needed for in‐lab polysomnography (PSG1) and home sleep apnea test Type 3 portable monitoring (HSAT) to accurately reflect the full‐night apnea–hypopnea index (AHI) in patients with suspected obstructive sleep apnea (OSA).
Raquel Chartuni Pereira Teixeira, Michel Burihan Cahali   +1 more
wiley   +1 more source