Results 131 to 140 of about 1,106,370 (306)

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Upper Mississippi River Restoration, Habitat Rehabilitation and Enhancement Project, Planning and Design Workshop: May 6-8, 2019, agenda

open access: yes, 2019
Leading •Innovating Partnering UPPER MISSISSIPPI RIVER RESTORATION HABITAT REHABILITATION AND ENHANCEMENT PROJECT PLANNING AND DESIGN WORKSHOP May 6-8, 2019 AGENDA Pre-Workshop Webinars (April/May) Habitat Needs Assessment-II Upper Mississippi River ...
Upper Mississippi River Restoration Program (U.S.);
core  

Early Warning and Risk Assessment for Rainfall-Induced Shallow Loess Landslides

open access: yesApplied Sciences
Rainfall-induced shallow loess landslides pose a significant threat to human life and property. Early warning and risk assessment of these landslides are critical prerequisites for engineering control and disaster loss reduction.
Feng Gao   +6 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Soil seed bank dynamics in transferred topsoil: Evaluating restoration potentials [PDF]

open access: yes, 2012
Global change, increasing human population growth and urbanisation represent increasing pressures on biodiversity and ecosystem function. It is now widely recognised that conservation of existing natural fragments will not be sufficient to maintain ...
Fowler, William
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Public summary of the Santa Monica Bay restoration plan

open access: yes, 1994
68 pgs.This report combines scientific characterization of the bay described in the Santa Monica Bay Restoration Plan report (1993) and other technical investigations. Recommendations for action which comprise the plan are discussed in full.
Santa Monica Bay Restoration Project
core  

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