Results 121 to 130 of about 830,111 (315)

Australian attitudes toward the protection and restoration of the Great Barrier Reef: Summary Findings

, 2022
This report presents the main results of the 2022 survey aimed to provide an understanding of Australian attitudes toward the development and deployment of novel restoration and adaptation options in the Great Barrier Reef (GBR), along with factors ...
Siehoyono Sie, Lintje, Lockie, Stewart, Ritchie, Brent W   +2 more
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Author Correction: Single compounds elicit complex behavioural responses in wild, free-ranging rats

Scientific Reports, 2018
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
Michael D. Jackson, Robert A. Keyzers, Wayne L. Linklater   +2 more
doaj   +1 more source

EcoTRADE : Investigating the suitability of tradable permits for biodiversity conservation in changing landscapes

, 2008
Habitat restoration has been employed in the context of ecological compensation, to offset negative impacts on ecosystems as a result of development projects.
Opdam, P.F.M., Teeffelen, A.J.A., van, Vos, C.C.   +2 more
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Landscape Dynamics of the Mu Us Sandy Land Based on Multi-Source Remote Sensing Images

Land
This study meticulously investigates landscape alterations within the Mu Us Sandy Land, a critical region for desertification control in China. The research dissects the dynamic characteristics and inter-conversion of landscape elements across eleven ...
Bingqiang Fei, Huirong Ma, Jie Yin, Lingguang Zhang, Jia Li, Xiaomin Xiu, Dezheng Zhou, Yingjun Pang, Yandong Zhang, Xiaohong Jia, Bo Wu   +10 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Early Warning and Risk Assessment for Rainfall-Induced Shallow Loess Landslides

Applied Sciences
Rainfall-induced shallow loess landslides pose a significant threat to human life and property. Early warning and risk assessment of these landslides are critical prerequisites for engineering control and disaster loss reduction.
Feng Gao, Yonghui Meng, Qingbing Wang, Jing He, Fanqi Meng, Jian Guo, Chao Yin   +6 more
doaj   +1 more source

Restoration of three indigenous forest types in Tauranga City, New Zealand

, 2013
This research examined the current state and developmental trajectory of forest restoration projects in Tauranga City with the aim of establishing whether they will eventually develop into functioning forest ecosystems similar to their natural ...
Dean, Hamish Alston
core