Results 21 to 30 of about 496,945 (249)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
(1) Background: The forest of Pinus sylvestris var. mongolica is an important semi-arid ecosystem in Hulunbuir sandy land that plays a key role in the carbon cycle and wind erosion control.
Shuo Wen +7 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
THE METHODOLOGICAL APPROACH IN THE MANAGEMENT OF CONSERVATION DATA FOR STUCCO ARTIFACTS
Some 90 Roman stucco fragments, coming from the Archaeological Park of Herculaneum, underwent in the conservation-restoration process within the Istituto Superiore per la Conservazione ed il Restauro (ISCR) laboratories in Matera. Before the conservation
Filippo Edoardo Capasso +9 more
doaj +1 more source
Lipidome analysis of milk composition in humans, monkeys, bovids, and pigs
Background Lipids contained in milk are an essential source of energy and structural materials for a growing neonate. Furthermore, lipids’ long-chain unsaturated fatty acid residues can directly participate in neonatal tissue formation.
Aleksandra Mitina +6 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
A new geodatabase of fuel treatments across federal lands in the USA
Catastrophic wildfires threaten landscapes across the United States, and fuel treatments are key to mitigating this risk. Yet, information regarding when, where, and what types of treatments have occurred is scattered across multiple systems of record ...
Anson Call +13 more
doaj +1 more source
Soil nutrient detection in wetlands is critical for rapidly and effectively managing these ecosystems. Our objective was to provide a methodological framework for identifying optimal data processing methods and machine learning model for predicting soil ...
Keying Qu +9 more
doaj +1 more source
RETHINKING MAIURI: ENHANCEMENT OF STUCCO FINDINGS FROM THE HERCULANEUM ARCHAEOLOGICAL PARKq
The subject of this study is a group of ninety stucco fragments from the Herculaneum Archeological Park, which were part of the decoration of the Tetrapylon’s barrel vault located in the Decumanus Maximus.
Filippo Edoardo Capasso +9 more
doaj +1 more source

