Results 41 to 50 of about 1,106,370 (306)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

A new geodatabase of fuel treatments across federal lands in the USA

Scientific Data
Catastrophic wildfires threaten landscapes across the United States, and fuel treatments are key to mitigating this risk. Yet, information regarding when, where, and what types of treatments have occurred is scattered across multiple systems of record ...
Anson Call, Nathan Tomczyk, Katahdin A. Withnall, Patricia R. Dappen, Dana Heusinkveld, Stephanie Mueller, Ben Holloway, Keaton Shennan, Jennifer Herring, Aidan Franko, Melanie M. Colavito, Aaron D. Kimple, Andrew Sánchez Meador, Camille S. Stevens-Rumann   +13 more
doaj   +1 more source

Vis–NIR Spectroscopy Characteristics of Wetland Soils with Different Water Contents and Machine Learning Models for Carbon and Nitrogen Content

Ecologies
Soil nutrient detection in wetlands is critical for rapidly and effectively managing these ecosystems. Our objective was to provide a methodological framework for identifying optimal data processing methods and machine learning model for predicting soil ...
Keying Qu, Leichao Nie, Lijuan Cui, Huazhe Li, Mingshuo Xiong, Xiajie Zhai, Xinsheng Zhao, Jinzhi Wang, Yinru Lei, Wei Li   +9 more
doaj   +1 more source

The Economics of Restoration [PDF]

, 2012
Macro-economic decisions determine the resources allocated at an international and a country-level to natural resource management. Micro-economic theory and tools are then used to ensure that this allocation will materialize into desired economic, environmental and societal outcomes. Restoration projects differ in their costs and benefits.
Wilson, Kerrie A., Lulow, Megan, Burger, Jutta, McBride, Marissa F.   +3 more
openaire   +4 more sources

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

People as Ecological Participants in Ecological Restoration.

, 2007
In 1987, Bradshaw proposed that ecological restoration is the ultimate “acid test” of our understanding the functioning of ecosystems (Bradshaw 1987).
Burke, S, Mitchell, ND
core   +1 more source

RETHINKING MAIURI: ENHANCEMENT OF STUCCO FINDINGS FROM THE HERCULANEUM ARCHAEOLOGICAL PARKq

Ochrona Dziedzictwa Kulturowego, 2019
The subject of this study is a group of ninety stucco fragments from the Herculaneum Archeological Park, which were part of the decoration of the Tetrapylon’s barrel vault located in the Decumanus Maximus.
Filippo Edoardo Capasso, Francesca Castiello, Simona Dichiara, Manuel Giandomenico, Natalie Iacopino, Erika Maddalena, Camilla Mauri, Sokol Muca, Mariagiulia Roscigno, Sofia Schiattone   +9 more
doaj   +1 more source

Light/dark phase influences intra-individual plasticity in maintenance metabolic rate and exploratory behavior independently in the Asiatic toad

BMC Zoology, 2022
Background It is well-known that light/dark phase can affect energy expenditure and behaviors of most organisms; however, its influences on individuality (inter-individual variance) and plasticity (intra-individual variance), as well as their ...
Song Tan, Juan Li, Qiao Yang, Jinzhong Fu, Jingfeng Chen   +4 more
doaj   +1 more source

Effect of Climate and Competition on Radial Growth of Pinus sylvestris var. mongolica Forest in Hulunbuir Sandy Land of Inner Mongolia, China

Plants, 2023
(1) Background: The forest of Pinus sylvestris var. mongolica is an important semi-arid ecosystem in Hulunbuir sandy land that plays a key role in the carbon cycle and wind erosion control.
Shuo Wen, Zhongjie Shi, Xiao Zhang, Leilei Pan, Semyung Kwon, Yuheng Li, Xiaohui Yang, Hanzhi Li   +7 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source