Results 61 to 70 of about 1,106,370 (306)

Four approaches to guide ecological restoration in Latin America

, 2016
There is strong upswing in conservation and restoration efforts in Latin America (LA), particularly in the recent decadesafter several countries have committed to international agreements such as the Aichi targets of the Convention on BiologicalDiversity,
Meli, Paula, Melo, Felipe, Minaverry, Clara, Aguirre, Nicolay, Musalem, Karim, Brancalion, Pedro SA, Herrera, Francisco F., Ramírez, Wilson, Pinto, Severino   +8 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

The Analysis of Spatial and Temporal Changes in Ecological Quality and Its Drivers in the Baiyangdian Watershed

Remote Sensing
As a critical ecological security node in North China, the Baiyangdian Basin underpins regional water resources, biodiversity conservation, and environmental risk mitigation.
Haoyang Wang, Chunyi Li, Meng Li, Yangying Zhan, Kexin Liu, Junxuan Li   +5 more
doaj   +1 more source

Structural and bio-functional assessment of the postaxillary gland in Nidirana pleuraden (Amphibia: Anura: Ranidae)

Zoological Letters, 2020
Background Owing to their incomplete adaptation to the terrestrial environment, amphibians possess complex cutaneous glandular systems. The skin glands not only regulate water loss and respiratory gas and salt exchange, but are also involved in defense ...
Yuzhou Gong, Yiwei Zeng, Puyang Zheng, Xun Liao, Feng Xie   +4 more
doaj   +1 more source

Restoration

Environment and Society
Abstract Ecological restoration practices and technologies are emerging as a dominant tool for addressing global environmental crises. This shift in conservation from a protectionist paradigm to a more hands-on approach signifies a new era of active intervention to the repair of ecosystems.
Pauwelussen, Annet P., Vandenberg, Jessica M.   +1 more
openaire   +2 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Articular cartilage debridement results in short-term significant improvements in patient-reported outcomes for large areas of cartilage loss of the femur in the setting of mild to moderate knee osteoarthritis

Journal of Cartilage & Joint Preservation
Introduction: Chondroplasty is a surgical option for chondral defects, but its effect on larger cartilage defects in the setting of knee osteoarthritis remains unclear.
Yusuf Mufti, Jared P. Sachs, Andrew S. Bi, Chloe Franzia, John Ebersole, Taylor Giordano, Brian J. Cole   +6 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source