Results 31 to 40 of about 496,945 (249)

Light/dark phase influences intra-individual plasticity in maintenance metabolic rate and exploratory behavior independently in the Asiatic toad

BMC Zoology, 2022
Background It is well-known that light/dark phase can affect energy expenditure and behaviors of most organisms; however, its influences on individuality (inter-individual variance) and plasticity (intra-individual variance), as well as their ...
Song Tan, Juan Li, Qiao Yang, Jinzhong Fu, Jingfeng Chen   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Alpine peatland degradation enhances soil nitrogen losses and alters plant nitrogen uptake strategies: evidence from nitrogen isotopes

Chemical and Biological Technologies in Agriculture
Background Nitrogen plays a critical role in sustaining ecosystem functions in peatlands; however, the degradation of approximately 12% of global peatlands substantially alters nitrogen cycling.
Xiaodong Zhang, Lijuan Cui, Xin Jia, Liang Yan, Yong Li, Zhongqing Yan, Kerou Zhang, Ao Yang, Yuechuan Niu, Enze Kang, Xiaoming Kang   +10 more
doaj   +1 more source

New Sample of Ancient Art from Kazakh Altay

Поволжская археология, 2019
In the paper, for the first time, the results of a laboratory study of a finding representing a fragment of a saddle coat are entered into a scientific circulation. Embroidery was being able to be reconstructed after 18 years since the discovery.
Altynbekov Krym, Zheleznyakova Vera L. , Altynbekova Elina K.   +2 more
doaj   +1 more source

Revealing of Intracellular Antioxidants in Dendrobium nobile by High Performance Liquid Chromatography-Tandem Mass Spectrometry

Metabolites, 2023
The medicinal plant Dendrobium nobile is an important natural antioxidant resource. To reveal the antioxidants of D. nobile, high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) was employed for metabolic analysis.
Dan Rao, Ruoxi Zhao, Yadong Hu, Hongjie Li, Ze Chun, Shigang Zheng   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Bone Marrow CD133 Stem Cells Ameliorate Visual Dysfunction in Streptozotocin-induced Diabetic Mice with Early Diabetic Retinopathy

Cell Transplantation, 2018
Diabetic retinopathy (DR), one of the leading causes of vision loss worldwide, is characterized by neurovascular disorders. Emerging evidence has demonstrated retinal neurodegeneration in the early pathogenesis of DR, and no treatment has been developed ...
Liyuan Rong, Xianliang Gu, Jing Xie, Yuxiao Zeng, Qiyou Li, Siyu Chen, Ting Zou, Langyue Xue, Haiwei Xu, Zheng Qin Yin   +9 more
doaj   +1 more source

Transcriptomics reveals the molecular processes of light-induced rapid darkening of the non-obligate cave dweller Oreolalax rhodostigmatus (Megophryidae, Anura) and their genetic basis of pigmentation strategy

BMC Genomics, 2018
Background Vertebrates use different pigmentation strategies to adapt to various environments. A large amount of research has been done on disclosing the mechanisms of pigmentation strategies in vertebrates either under light, or, living in constant ...
Wei Zhu, Lusha Liu, Xungang Wang, Xinyu Gao, Jianping Jiang, Bin Wang   +5 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source