Results 101 to 110 of about 395,262 (311)

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Biomass Exhibited Greater Sensitivity to Degradation Than Community Structure in an Alpine Meadow

Ecology and Evolution
Clarifying the temporal sequence of productivity loss and community structure alteration is critical for developing effective grassland restoration strategies.
Huimin Wu, Haitao Yue, Yong Zhang, Kaiting Wu, Xiaorong Wang, Jianing Li, Jinyao Li, Hao Zeng   +7 more
doaj   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

A Data Driven Review of In Vitro Electrical and Mechanical Stimulation for Post‐Acute Phase Wound Healing

Advanced Healthcare Materials, EarlyView.
This review examines how in vitro electrical and mechanical stimulation modulates wound healing in fibroblasts and keratinocytes. Analyzing over 560 experimental data points, we relate stimulation parameters to proliferation and migration outcomes, evaluate platform designs, and highlight the need for multi‐parameter optimization to advance targeted ...
Matthew K. Burgess, Ellen F. Marsh, Veronica M. Lucian, Malavika Nair   +3 more
wiley   +1 more source

Biodiversity offsets can be a valuable tool in achieving sustainable development: Developing a holistic model for biodiversity offsets that incorporates environmental, social and economic aspects of sustainable development [PDF]

, 2019
The interpretation and use of biodiversity offsets in planning and development is a contentious issue because they rarely encompass each of the environmental, social and economic aspects of sustainable development.
Abdo, Linda, Coupland, Grey, Griffin, Sandy, Kemp, Annabeth   +3 more
core   +1 more source

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

Advanced Materials, EarlyView.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen, Gao Wei, Guowei Zeng, Haoyu Li, Rongrong Wu, Hongyu Yan, Zijie Zhou, Kai Luo, Xiaoyang Zhang, Cong Li, Longming Huang, Lingyan Cheng, Xinjie Zhang, Jinghao Zheng, Bozhong Shi, Xiaojun Cai, Xiaomin He   +16 more
wiley   +1 more source

Prioritising investment to enhance biodiversity in an agricultural landscape [PDF]

The removal, alteration and fragmentation of habitat are key threats to the biodiversity of terrestrial ecosystems. Investment to protect biodiversity assets (e.g. restoration of native vegetation) in dominantly agricultural landscapes usually results in
Pannell, David J., Park, Geoff, Polyakov, Maksym, Roberts, Anna M., Rowles, Alexei   +4 more
core   +1 more source

Panama City Fisheries Resources Office: FY 2002 Annual Report [PDF]

, 2003
HIGHLIGHTS FOR FY 2002 1. United States Senator Bob Graham assisted with a Gulf sturgeon survey. 2. Completed 3-year Gulf sturgeon population study in the Choctawhatchee River drainage. 3. Completed Gulf sturgeon potential spawning habitat survey for

core  

Matrix Viscoelasticity Regulates Dendritic Cell Migration and Immune Priming

Advanced Materials, EarlyView.
Matrix viscoelasticity is a key mechanical feature of the tumor microenvironment but remains poorly understood in immune regulation. Here, we develop a tunable collagen platform to decouple viscoelasticity from stiffness and show that slow‐relaxing matrices constrain dendritic cell migration by limiting actomyosin‐driven matrix remodeling, thereby ...
Wei‐Hung Jung, Emie Humann, Joshua M. Price, Yoav Binenbaum, Azra Haseki, Sanjana Iyer, David J. Mooney   +6 more
wiley   +1 more source

Spatial Distribution Patterns of Dominant Tree Species and Their Associations with Soil Factors in Subalpine Secondary Forests of Western Sichuan

Plants
Spatial pattern analysis is essential for understanding forest structure and successional dynamics. Focusing on natural secondary forests in the subalpine region of western Sichuan, China, we established two 1-hectare permanent plots to investigate the ...
Jingdong Zhao, Xin Liu, Le Wang, Qiuhong Feng, Chang Gou, Jianhua Bai, Xiaohui Yang   +6 more
doaj   +1 more source