Results 121 to 130 of about 395,262 (311)

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

Chromosome-level genome assembly for clubrush (Scirpus × mariqueter) endemic to China

Scientific Data
Scirpus × mariqueter (Tang & F.T.Wang) Tatanov, which is endemic to eastern estuaries in China, is a tidal zone-engineering species with great promise for managing greenhouse gases and enhancing ecosystem resilience against invasive species.
Yu Ning, Yang Li, Chun Yi Li, Jin Zhi Wang, Tian Shi Wang, Yan Chao Zheng, Yang Ying Zhan, Shen Jian Xu, Shu Bin Dong, Yi Fei Wang   +9 more
doaj   +1 more source

Quality Assessment and Identification of Key Areas for Ecological Conservation Projects in Inner Mongolia

Land
In the context of global climate change, implementing ecological projects in China is critical for improving ecosystem quality, conservation, and sustainable development.
Tianqi Li, Panyu Chen, Jiayi Lin, Quanlong Wu, Hailin Zhang, Jinyan Zhan   +5 more
doaj   +1 more source

LOCATION-SPECIFIC MODELING FOR OPTIMIZING WILDLIFE MANAGEMENT ON CROP FARMS [PDF]

In order to guide conservation and restoration of wildlife in agricultural areas research is needed into the trade-off between wildlife and agricultural production and income.
Renkema, Jan, van Wenum, Jaap, Wossink, Ada   +2 more
core   +1 more source

Planning Preservation In Pompeii: Revising Wall Painting Conservation Method And Management [PDF]

, 2013
The management of Pompeii’s focus on excavation and tourism has caused its wall art to fall into disrepair, but a new focus on efficiency and sustainable practice has the potential to relieve the emergency of Pompeii’s restoration work. Hasty excavations,
Wollner, Jennifer L
core   +1 more source

Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1

Advanced Science, EarlyView.
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency, Tao Cui, Yimei Cai, Chloe Lok, Rachel E. Nokku, Ruoxian Huang, Grace L. Chu, Yumeng Xie, Saleem W. Abu‐Tayeh, Kaikai He, Chengjie Qiu, Junyi Wang, Paxton M. Paganelli, Ting Wang, Gabrielle Williams, Sreejith Nair, Huadong Pei, Dion K. Dickman, Stefano Vicini, Tingting Wang   +19 more
wiley   +1 more source

Restoration of endangered epiphytic lichens in fragmented forest landscapes [PDF]

, 2009
In a situation with increasingly rapid changes in landscape mosaics, driven by large-scale forestry and future climate change, a number of epiphytic lichens are now becoming threatened.
Lidén, Marlene
core  

ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells

Advanced Science, EarlyView.
With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao, Shannon Erhardt, Li Tang, Xiaotong Chen, Stephen M Farmer, Zixiu Cheng, Wen Chen, Ella Ziyuan Lu, Kihan Sung, Chang‐Ru Tsai, Mingjie Zheng, Sheng Zhang, Yang Liu, Jianxin Wang, Min Li, James F Martin, Jun Wang   +16 more
wiley   +1 more source

Preliminary comparison of natural versus model-predicted recovery of vessel-generated seagrass injuries in Florida Keys National Marine Sanctuary [PDF]

, 2009
Each year, more than 500 motorized vessel groundings cause widespread damage to seagrasses in Florida Keys National Marine Sanctuary (FKNMS). Under Section 312 of the National Marine Sanctuaries Act (NMSA), any party responsible for the loss, injury, or ...
Fonseca, Mark S., Kenworthy, W. Judson, Uhrin, Amy V.   +2 more
core  

LC3B Mediated SETDB1‐Accounted Alcoholic Steatohepatitis via Lipidation‐Dependent LAP and Lipidation‐Independent Nuclear Stabilization

Advanced Science, EarlyView.
SETDB1 is progressively downregulated in ALD, correlating with disease severity. SETDB1 deficiency impairs LAP by disrupting Rubicon membrane localization, leading to defective lipid droplet clearance. Concurrently, loss of SETDB1 reduces nuclear LC3B, causing R‐loop accumulation and cGAS‐STING‐driven inflammation. Lipidated LC3B mediates LAP‐dependent
Yi Zhang, Tan Wei, Jiahang Wu, Chuixu Lin, Dongbo Zhu, Yanhui Li, Shuting Shi, Shishun Huang, Leiming Jiang, Hongzhi Wang, Meiqi Song, Pengfei Gao, Xu Wu, Mingjian Fan, Chaofeng Wei, Qian Wang, Lihui Qu, Zhigang Wang   +17 more
wiley   +1 more source