Results 131 to 140 of about 36,469 (301)

Perancangan Panti Wreda Pengayoman dengan Konsep Restorative Environment [PDF]

Indonesia merupakan negara dengan populasi penduduk terbesar keempat di dunia, dengan sekitar 10,48% dari populasi adalah lansia. Untuk memenuhi kebutuhan sehari-hari para lansia, pemerintah dan swasta kemudian memberikan fasilitas berupa tempat ...
Michelle Hantono, Caryn
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A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Research on Restorative Benefits and Stress Relief Approaches in Urban Green Space for Different Stress Threshold Groups

Land
Urban green spaces, as vital land use components, play a crucial role in promoting public mental health and well-being. This study investigates the differential restorative benefits and stress relief pathways in urban green spaces for populations with ...
Yujiao Li, Zihan Xu, Jie Yang
doaj   +1 more source

A novel bioactive nano-composite: synthesis and characterisation with potential use as dental restorative material

, 2009
PhDIt is desirable for a dental restorative material to have bioactive and bonding properties. This study focuses on the synthesis of a covalently-linked polyurethane/nanohydroxyapatite (PU/nHA) composite and evaluates its chemical, physical, thermal ...
Khan, Abdul Samad
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

The Influence of Campus Landscape Color Environment on Students’ Emotions: A Case Study of Shandong Agricultural University

Buildings
As the daily activity space for students, the external campus environment directly impacts their physical and mental health. While previous studies have demonstrated the restorative effects of outdoor environments on emotional recovery and stress relief,
Yingjie Li, Ying Yu, Dingmeng Hu, Xinyue Shang, Tianyu Wang, Keran Liu, Siwei Mou, Xinwen Zhang   +7 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

How can vegetation landscapes enhance the health benefits of visual exposure to urban forests? An analysis of ecological, colour and spatial factors

Frontiers in Forests and Global Change
IntroductionRapid urbanisation exacerbates psychological stress and diseases, highlighting the critical role of urban forests in mitigating health challenges.
Kaiyuan Yi, Jinyu Zhang, Yuhui Hao, Zhiheng Li, Zhe Zhang   +4 more
doaj   +1 more source

Urban park soundscapes and their perceived restorativeness [PDF]

, 2010
Individual sounds and soundscapes can influence individuals, their place evaluations and potentially their psychological restoration. As urban park soundscapes can vary greatly, ranging from quiet, serene oases to noisy city spaces, it is important to ...
Payne, Sarah R., Payne, Sarah R
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