Results 71 to 80 of about 32,432 (259)

Urban landscape as a restorative environment: preferences and design considerations

Acta Agriculturae Slovenica, 2006
In this paper, the idea of considering public preferences in design of urban landscapes as restorative environments is explored. A visual landscape preference research was conducted among user groups in Slovenia.
Tanja SIMONIČ
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Empirical Study on Emotional Perception and Restorative Effects of Suzhou Garden Landscapes: Text Mining and Statistical Analysis

Land
Suzhou classical gardens, as a unique form of urban green space in China, not only embody rich historical and cultural heritage but also showcase distinctive natural landscapes, exerting a profound impact on modern mental health.
Zhenyu Zhang, Xiaomeng Wang, Mu Jiang
doaj   +1 more source

Exploring the Physiological and Psychological Effects of Digital Shinrin-Yoku and Its Characteristics as a Restorative Environment. [PDF]

Int J Environ Res Public Health, 2022
Takayama N, Morikawa T, Koga K, Miyazaki Y, Harada K, Fukumoto K, Tsujiki Y.   +6 more
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Enhancing Cognitive Performance and Physiological Benefit in Workspaces Through Patterns of Biophilic Design: A Restorative Approach

Buildings
Contact with nature is believed to enhance mental health through the process of human psychological restoration. However, prolonged indoor living limits individuals’ exposure to nature, potentially hindering the timely alleviation of stress and fatigue ...
Ping Zhang, Zhengqi Yu, Guoying Hou, Ping Shu, Yunque Bo, Yankun Shi, Rui Nie   +6 more
doaj   +1 more source

Regulating effect of virtual reality restorative environment on prefrontal cortex dysfunction after night shifts in medical staff: an fNIRS study protocol for a randomized controlled trial in Dalian, China. [PDF]

Trials, 2023
Huang X, Song C, Jiang Y, Liang Z, Qu X, Fu S.   +5 more
europepmc   +1 more source