Results 81 to 90 of about 36,469 (301)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Restoring ecological complexity in a changing environment

Current Biology
As land use leaves massive tracts of land vacant for recovery, restoration must undergo a substantial shift to incorporate a complexity perspective beyond the traditional community, biodiversity or functional views. With an interaction-function perspective, we may be able to achieve ecosystems with better chances to adapt to current environmental ...
Moreno Mateos, D, Bhatnagar, JM
openaire   +3 more sources

An Interdisciplinary Theoretical Interpretive Synthesis Examining the Barriers to Implementing Restorative Justice as the Standard Paradigm of Adult Criminal Justice Within the Context of the United States

, 2010
A systemic paradigm shift of any sort is complex and multifaceted. A systemic paradigm shift of justice is no different. The purpose of this study is to identify the barriers that exist in a systemic paradigm shift from retributive justice to restorative
Van Maastricht, Matthew J., van Maastricht, Matthew J   +1 more
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Relaxing at work: does virtual reality work? An exploratory study among employees in their workplace

Frontiers in Organizational Psychology
IntroductionThe development of virtual reality provides new opportunities for conducting relaxing activities in a simulated environment. Although studies on the effects of VR-based relaxation are developing, they have mostly been performed with students,
Estelle Michinov, Virginie Dodeler, Hugo Adam, Nicolas Michinov   +3 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

Urban landscape as a restorative environment: preferences and design considerations

Acta Agriculturae Slovenica, 2006
In this paper, the idea of considering public preferences in design of urban landscapes as restorative environments is explored. A visual landscape preference research was conducted among user groups in Slovenia.
Tanja SIMONIČ
doaj   +1 more source

Hikoitanga tapuwae o te hunga ke To take a walk in another's shoes: Using process drama to teach the underlying principles of restorative practice

, 2012
Hikoitanga tapuwae o te hunga ke To take a walk in another’s shoes Using process drama to teach the underlying principles of restorative practice. An increasing number of schools in New Zealand are changing the way they work with at risk students by ...
Bleaken, Susan
core  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source