Results 51 to 60 of about 19,670 (297)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

A review of restorative justice responses to offending [PDF]

open access: yes, 2013
Restorative justice has been enthusiastically embraced in many justice systems as an alternative to incarceration for young adult and Indigenous offenders. But how well does it work?
Megan Macadam, Don Weatherburn
core  

Restorative Justice

open access: yes, 2009
Restorative justice is an umbrella term for a victim-oriented method of righting a wrong, promoting healing following conflict, and providing a sense of safety in the aftermath of violence. Restorative justice refers not only to a number of strategies for resolving conflicts peacefully but also to a political campaign of sorts to ...
  +4 more sources

Penerapan Restorative justice Dalam Undang-Undang No 1 Tahun 2023 Tentang Kitab Undang-Undang Hukum Pidana: Perspektif Regulator Dan Aparat Penegak Hukum

open access: yesAsas wa Tandhim
Restorative justice policies in Indonesia are still scattered across several regulations. This study aims to examine the importance of restorative justice implementation regulations in resolving criminal cases in Indonesia, as well as to determine the ...
Mustolih Mustolih, Faqih Zuhdi Rahman
doaj   +1 more source

The ‘afw Principle and The Indonesian Restorative Justice System

open access: yesJurnal Hukum Islam, 2021
This paper explains the implementation of the ‘afw  principle, a forgiveness principle known in Islamic criminal law, as an objective of Restorative Justice.
Muhammad Rijaldy Alwy Alwy
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Restorative Justice: Pemaknaan, Problematika, dan Penerapan yang Seyogianya

open access: yesUnes Journal of Swara Justisia
Pendekatan restorative justice merupakan tonggak pembaharuan reformasi sistem hukum pidana ke arah positif. Namun dewasa ini, sistem hukum pidana Indonesia belum mengakomodasi penjelasan secara komprehensif mengenai definisi, prinsip, serta penerapan ...
Muhammad Rif'an Baihaky   +1 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Oral language competence and restorative justice processes: refining preparation and the measurement of conference outcomes [PDF]

open access: yes, 2013
Restorative justice conferencing for young offenders is a legislated response to youth offending, which has been in place in all Australian states and territories for nearly two decades.
Pamela Snow, Hennessey Hayes
core  

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