Results 141 to 150 of about 54,423 (265)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Mechanical and Surface Behavior of Contemporary Restorative Materials Exposed to Topical Hemostatic Agents After Artificial Aging: An In Vitro Study. [PDF]

Polymers (Basel)
Kaya İ, Yıldırım SN, Demirel A.
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

An in vitro comparison of color stability between alkasite and different restorative materials in various staining solutions. [PDF]

Sci Rep
Ağaccıoğlu M, Yılmaz MN, Bulut ES.
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Biomimetic Design of Dental Restorative Materials: Conceptual Framework and Translational Challenges. [PDF]

Biomimetics (Basel)
Alluhaidan T, Hung B, Qaw M, Garcia IM, Melo MAS.   +4 more
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

The Effects of Bioactive Glass-Containing Toothpastes on <i>Streptococcus mutans</i> Biofilm Removal from Contemporary Restorative Materials: An In Vitro Study. [PDF]

Dent J (Basel)
Isfendiyaroglu I, Daniskan AS, Bagkur C, Ozverel CS, Isfendiyaroglu M, Ergucu Z.   +5 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Comparison of the Effect of Simulated Gastric Acid on the Surface Properties of Different Fluoride-Releasing Dental Restorative Materials. [PDF]

Oral Health Prev Dent
Romero-Cabrera L, Teutle-Coyotecatl B, Flores-Ledesma A, Jiménez-Flores R, Sol-Gamboa MG, Contreras-Bulnes R, Rodríguez-Vilchis LE, de Anda-Reyes E, de Los Angeles Moyaho-Bernal M.   +8 more
europepmc   +1 more source