Results 81 to 90 of about 2,720,038 (247)

Development and use of a two-gene marker-aided selection system for fertility restorer genes in rice

, 2006
We have established marker-aided selection strategies for the two major Rf genes (Rf3 and Rf4) governing fertility restoration of cytoplasmic-genetic male sterility (CMS) in rice.
Gregorio, Glenn B., Virmani, Sant S., Kathiresan, Arumugam, Hernandez, Jose E., Nas, Tamerlane M., Sattari, Majid   +5 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Genome-wide analysis of Rf-PPR-like genes in Nicotiana tabacum and their potential roles in anther development

Frontiers in Plant Science
Pentatricopeptide repeat (PPR) gene family is one of the largest gene families in higher plants. The Restoration of fertility like (RFL) clade of the family plays a crucial role in restoring fertility of cytoplasmic male sterility (CMS) lines in plants ...
Mengting Wu, Yan Ji, Chengbei Zhang, Shuaibin Du, Ruqi Gong, Jun Wang, Jiayi Li, Qiu Zhong, Yuan Li, Aiguo Yang, Yazhi Cheng, Xingwei Zhang, Guoxiang Liu   +12 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Silencing of fertility restoration genes in sunflower

Helia, 2003
Single dominant genes for fertility restoration of cytoplasmic male-sterile Cms ANN2 have been identified in PI 413178, P21, and RCMG3, while PI 413180 P21, RHA801, RCMG1, and RHA280 were identified as restoration sources for cmsANN3. However, some cms plants were observed in progenies of homozygous restoration lines crossed with HA89, RHA266, and ...
openaire   +2 more sources

Gene Therapy Strategies to Restore ER Proteostasis in Disease

Molecular Therapy, 2018
Proteostasis alterations are proposed as a transversal hallmark of several pathological conditions, including metabolic disorders, mechanical injury, cardiac malfunction, neurodegeneration, and cancer. Strategies to improve proteostasis aim to reduce the accumulation of specific disease-related misfolded proteins or bolster the endogenous mechanisms to
Valenzuela, Vicente, Jackson, Kasey L., Sardi, Sergio P., Hetz Flores, Claudio   +3 more
openaire   +3 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Identification and inheritance of fertility restorer genes for 'tour' CMS in rapeseed (Brassica napus L.)

, 1994
Eighteen genotypes of Brassica napus were crossed to a cytoplasmic male sterile (CMS) line of B. napus BO 15 carrying B. tournefortii cytoplasm ('tour' cytoplasm). Fourteen genotypes were found to be stable maintainers of the 'tour' CMS. Of the remaining
Verma, J. K., Arumugam, N., Pental, D., Sodhi, Y. S., Mukhopadhyay, A., Pradhan, A. K.   +5 more
core   +1 more source

Significant association of the novel Rf4-targeted SNP marker with the restorer for WA-CMS in different rice backgrounds and its utilization in molecular screening

Journal of Integrative Agriculture, 2017
: In the rice cytoplasmic-genetic male sterility (CMS) system, the combination of a CMS line, maintainer line and restorer line carrying the restorer gene to restore fertility, is indispensable for the development of hybrids.
Li-kai CHEN, Xian-cheng YAN, Jun-hao DAI, Si-ping CHEN, Yong-zhu LIU, Hui WANG, Zhi-qiang CHEN, Tao GUO   +7 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source