Results 61 to 70 of about 2,720,038 (247)
Gene therapy to restore electrophysiological function in heart failure [PDF]
Expert Opinion on Biological Therapy, 2015 Heart failure (HF) is a major public health epidemic and a leading cause of morbidity and mortality in the industrialized world. Existing treatments for patients with HF are often associated with pro-arrhythmic activity and risk of sudden cardiac death.
Lukas J, Motloch, Fadi G, Akar
openaire +2 more sources
, 2002 Since the suggestion concerning the hypothesis of the existence of restorer cytoplasms for some of the known and currently available male sterile (ms) genes in maize, a relatively limited amount of research effort has been made in order to test the ...
Vidaković, M.B. +2 more
core +1 more source
COMBINING ABILITY STUDIES FOR GRAIN YIELD AND SOME ASSOCIATED CHARACTERS IN SOME RICE LINES [PDF]
Journal of Plant Production, 2014 This study was conducted at Rice Research and Training Center (RRTC), of Farm Sakha - KafrelSheikh, Egypt, during the summer seasons of 2010 , 2011 and 2012 to investigate the combining ability of some parental lines in their crosses.
M. El-Shenawy +3 more
doaj +1 more source
Cut and Paste: restoring cellular function by gene correction [PDF]
Cell Research, 2011 Gene-editing technologies and patient-specific induced pluripotent stem cells (iPSCs) may represent an unprecedented opportunity for merging the stem cell and traditional gene therapy fields to fulfill the promises of regenerative medicine.
Liu, Guang-Hui +2 more
openaire +3 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
, 1989 The inheritance of male fertility restoration for the pol cytoplasmic male sterility (CMS) system in summer rape (Brassica napus L.) was determined.
P. B. E. McVetty, G. H. Fang
core +1 more source
Journal of BioScience and Biotechnology, 2017 Heterosis is related to genetic diversity among the parental lines, which is considered to be important for the development of superior hybrids. The objective of this study was to characterize 145 genotypes of post-rainy sorghum comprising of 40 ...
Passoupathy Rajendrakumar +5 more
doaj
The Plant Genome, 2020 The maize C system of cytoplasmic male sterility (CMS) and its fertility restoration gene Rf4 have been widely used for maize hybrid production; however, the underlying mechanism is still uncertain.
Huaisheng Zhang +7 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
, 2020 Two popular stable restorer lines, CB 87 R and CB 174 R, were improved for blast resistance through marker-assisted back-cross breeding (MABB). The hybrid rice development program in South India extensively depends on these two restorer lines.
Ganesh Alagarasan +5 more
core +1 more source