Results 51 to 60 of about 478,764 (229)
Public Schooling for Democracy. A Book Review of \u3cem\u3ePublic Education: Defending a Cornerstone of American Democracy\u3c/em\u3e [PDF]
This essay is a book review of Public Education: Defending a Cornerstone of American ...
Reid, Ellis E, V
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Advanced Science, EarlyView.Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon +27 more
wiley +1 more source
Schooling for Democracy: A Common School and a Common University? A Response to “Schooling for Democracy” [PDF]
, 2011 This short paper is a response to Nel Noddings’s article on schooling for democracy. Whilst agreeing with the basic premises of Noddings’s argument, it questions the possibility of parity between academic and vocational tracks given the inequitable ...
Reay, Diane
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Advanced Science, EarlyView.We developed an ultrasound‐controlled biomimetic nanoplatform, mRNA/V@M NPs, to co‐deliver CD74 mRNA and V‐9302 for fibrotic TNBC therapy. CD74 mRNA reprograms myCAFs into antigen‐presenting apCAF cells through the CD74‐MHC II pathway, while V‐9302 induces ICD and activates MHC I‐CD8+ T cell immunity.
Chen Ai +9 more
wiley +1 more source
Searching for the Path to a More Perfect Union. A Book Review of \u3cem\u3eEducating for Democracy\u3c/em\u3e [PDF]
Educating for Democracy presents Walter Feinberg’s vision for the democratic aims of education. Feinberg argues that the evolutionary nature of democracy should be met with a citizenry capable of critical reflection.
McCullough, Aaron +3 more
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Advanced Science, EarlyView.The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang +12 more
wiley +1 more source
Advanced Science, EarlyView.Inspired by the intricate microstructure of cicada wings, researchers developed a novel in situ skeleton‐graphene membrane architecture within lightweight foams. This bioinspired design dramatically enhances multifunctional performance: vibration attenuation time decreases by ∼83.3%, damping capacity increases by ∼179.3%, and compressive modulus rises ...
Jigang Feng +6 more
wiley +1 more source
Presentación: La Historia continúa
Historia Actual On-Line, 2008 Por fortuna para quienes humildemente cultivamos este conocimiento, la Historia continúa. Las utopías finalistas que hace sólo una década inundaron el mercado de la letra impresa han sido borradas de un plumazo por la tozudez de los hechos.
Julio Perez Serrano
doaj
Advanced Science, EarlyView.Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie +12 more
wiley +1 more source
Advanced Science, EarlyView.USP30 accumulation in diabetic renal tubular epithelial cells deubiquitinates PEX5, suppresses pexophagy, and drives dysfunctional peroxisome accumulation and tubular injury. USP30 depletion restores PEX5 ubiquitination and pexophagy, improves peroxisomal function, and alleviates tubular damage, highlighting USP30 as a therapeutic target in diabetic ...
Jia Li +10 more
wiley +1 more source