Results 71 to 80 of about 175,570 (302)

Analytical Model for Angular Distortion in Multilayer Welding under Constraints

Applied Sciences, 2020
We propose an analytical model for the fast prediction of angular distortion that is caused by practical multilayer (or multi-pass) butt welding under constraints.
Woo-Jae Seong, Sang-Cheol Park, Hee-Keun Lee   +2 more
doaj   +1 more source

DIRECT AND COLLATERAL EFFECTS OF RESTRAINTS AND RESTRAINT FADING [PDF]

Journal of Applied Behavior Analysis, 1997
Mechanical restraints are commonly used to reduce the risks associated with severe self‐injurious behavior (SIB), but may result in movement restriction and adverse side effects (e.g., bone demineralization). Restraint fading may provide a method for decreasing SIB while increasing movement and reducing these side effects. In the current investigation,
W W, Fisher, C C, Piazza, L G, Bowman, G P, Hanley, J D, Adelinis   +4 more
openaire   +2 more sources

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

How Farm Animals React and Perceive Stressful Situations Such As Handling, Restraint, and Transport

Animals, 2015
An animal that has been carefully acclimated to handling may willingly re-enter a restrainer. Another animal may have an intense agitated behavioral reaction or refuse to re-enter the handling facility.
Temple Grandin, Chelsey Shivley
doaj   +1 more source

Restraints Rock

Nursing Management (Springhouse), 2000
Restraint issues can create problems for staff, patients, and family. To meet the Joint Commission's restraint rules, a multidisciplinary education plan included alternative and distractive devices for patients. Use of restraints decreased markedly as staff members' knowledge and attitude improved.
K, Missildine, S, Harvey
openaire   +3 more sources

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Part 1: Assessment of upright restraint of broilers for head-only electrical stunning

Animal Welfare
The welfare issues associated with water-bath stunning, particularly inversion and shackling, are widely recognised. This study aimed to develop, optimise and evaluate a prototype upright restraint system for broilers that avoids inversion and shackling ...
Troy J. Gibson, Georgina Limon, Shannon Campbell, Natalie Chancellor, Katharine A Fletcher, Paul Berry, Jeff Lines   +6 more
doaj   +1 more source

Demonstrating Restraint

CoRR
Some have claimed that the future development of powerful AI systems would enable the United States to shift the international balance of power dramatically in its favor. Such a feat may not be technically possible; even so, if American AI development is perceived as a sufficiently severe threat by its nation-state adversaries, then the risk that they ...
L. C. R. Patell, O. E. Guest
openaire   +3 more sources

Phenomenology of Self-Restraint [PDF]

American Journal on Mental Retardation, 2003
Self-restraint is often reported in individuals with mental retardation who show self-injurious behavior (SIB). In this study, the phenomenology and prevalence of self-restraint in individuals showing self-injury and wearing protective devices and those showing self-injury but not wearing protective devices were compared.
Oliver, C, Murphy, G, Hall, S, Arron, K, Leggett, J   +4 more
openaire   +3 more sources

Debriefing Following Seclusion and Restraint: A Summary of Relevant Literature [PDF]

, 2014
This report provides a summary of current debriefing practices that have been shown to support strategy six in the Six Core Strategies© and supports seclusion or restraint reduction programmes, drawn from a review or relevant literature.
Sutton, D, Webster, S, Wilson, M
core