Results 81 to 90 of about 175,570 (302)

Protecting the innocent, the land, and the body : traditional sources of restraint on landmine use

, 2023
What drives restraint in armed conflict? Recent studies have examined different factors contributing to restraint behaviour, mainly focusing on strategic incentives, such as seeking legitimacy from international audiences or securing support from local ...
Breay Bolton, Matthew,, Siniciato Terra Garbino, Henrique,   +1 more
core  

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Part 2: Behavioural and electroencephalographic assessment of upright restraint and head-only electrical stunning of broilers

Animal Welfare
The majority of small- to medium-scale and Halal poultry processors still rely on electrical water-bath stunning, despite recognised concerns regarding its humaneness and effectiveness.
Troy J. Gibson, Georgina Limon, Shannon Campbell, Natalie Chancellor, Katharine A. Fletcher, Paul Berry, Jeff Lines   +6 more
doaj   +1 more source

Creatine kinase activity in the assessment of muscle injuries following lateral recumbency and standing restraint positions for rumenotomy in kano-brown goats [PDF]

Eurasian Journal of Veterinary Sciences, 2020
Aim: The study was to evaluate and establish the comparative advantages offered by two conventional lateral recumbence rumenotomy techniques and a locally fabricated mobile small ruminant chute for standing position rumenotomy based on the profiles of ...
Abubakar Mshelia Saidu, Samuel Tanko Fadason, Gabriel Enenche Ochube, Sani Adamu   +3 more
doaj  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Improving pain score and restraint duration during circumcision

Journal of Family Medicine and Primary Care
The American Academy of Pediatrics (AAP) recommends providing adequate analgesia during circumcision. Ring block is the most effective method of analgesia, while topical crème (EMLA: lidocaine and prilocaine topical) alone is ineffective.
Ramzi A. Kilani
doaj   +1 more source

The Wisdom of Restraint

JACC: Cardiovascular Interventions, 2018
I was pleased to see the thoughtful editorial by Dr. Chris White [(1)][1] in a recent issue of JACC: Cardiovascular Interventions . I remember the case Dr. White describes very well, and it reminded me of the many lessons we have learned about product development over the past 40 years.
openaire   +2 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Integritas Personal dan Kepemimpinan Etis

Humaniora, 2014
Integrity is very important for a leader. When a leader does not have integrity, then, sooner or later it will destroy the group or organization s/he leads. This occurs because the policies, decisions, attitudes, and actions made by the leader will have
Antonius Atosökhi Gea
doaj