Results 101 to 110 of about 5,213,227 (370)

Restricted Families of Projections and Random Subspaces [PDF]

Real Analysis Exchange, 2018
We study the restricted families of orthogonal projections in $\mathbb{R}^3$. We show that there are families of random subspaces which admit a Marstrand- Mattila type projection theorem.
openaire   +3 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Correlated Randomness Reduction in Domain-Restricted Secure Two-Party Computation

, 2023
Keitaro Hiwatashi, Koji Nuida
openalex   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Exploring optimal serum selenium range for heart failure prevention: A U-shaped association and mediation by hepatic steatosis in US adults

Journal of International Medical Research
Objective The relationship between serum selenium levels and heart failure risk remains unclear. This study aimed to investigate the potential nonlinear association between serum selenium level and heart failure risk and explore whether hepatic steatosis
Han Li, Wenhu Liu, Jingjie Xiong, Xuehua Wang, Qian Xu, Ni Xiong, Yanling Huang, Yan Wang, Jing Hu, Zhaohui Wang   +9 more
doaj   +1 more source

Anxiety—depression: a pivotal mental factor for accelerating disease progression and reducing curative effect in vitiligo patients

Frontiers in Psychology
ObjectiveTo clarify the causal relationship between anxiety-depression and the progression and outcomes of vitiligo, providing a basis for enhancing psychological interventions in the treatment of vitiligo.MethodsA two-sample Mendelian randomization ...
Cheng Cao, Cheng Cao, Fuquan Lin, Rong Jin, Jindi Lei, Jindi Lei, Yujie Zheng, Yujie Zheng, Anqi Sheng, Wen Xu, Aie Xu, Miaoni Zhou   +11 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Integrated Retrospective and Post‐GWAS Analyses Reveal Mechanisms Linking Nightly Short Sleep to Asthma

Brain and Behavior
Objectives This study employs a dual‐pronged approach, integrating retrospective cohort analysis with genetic methodologies, to elucidate the causal role of nightly short sleep in the pathogenesis of asthma and to unravel its underpinning biological ...
Chong Fu, Wei Xu, Yanping Zhang
doaj   +1 more source

Effects of 4- and 6-h Time-Restricted Feeding on Weight and Cardiometabolic Health: A Randomized Controlled Trial in Adults with Obesity [PDF]

, 2020
Sofia Cienfuegos, Kelsey Gabel, Faiza Kalam, Mark Ezpeleta, Eric Wiseman, Vasiliki Pavlou, Shuhao Lin, Manoela Lima Oliveira, Krista A Varady   +8 more
openalex   +1 more source