Results 41 to 50 of about 142,506 (314)

Enhanced Convergence and Robust Performance of Randomized Dynamical Decoupling [PDF]

open access: yes, 2006
We demonstrate the advantages of randomization in coherent quantum dynamical control. For systems which are either time-varying or require decoupling cycles involving a large number of operations, we find that simple randomized protocols offer superior ...
A. Beige   +4 more
core   +3 more sources

Maternal vitamin D during pregnancy and offspring autism and autism-associated traits: a prospective cohort study

open access: yesMolecular Autism, 2022
Background There has been a growing interest in the association between maternal levels of vitamin D during pregnancy and offspring autism. However, whether any associations reflect causal effects is still inconclusive.
Paul Madley-Dowd   +9 more
doaj   +1 more source

RESTRICTED DEVICE DATA SANITIZATION AND RANDOMIZATION [PDF]

open access: yes, 2020
Presented herein is a Trusted Access Platform (TAP) that assists customers with highly restricted data access to solve their business critical challenges.
Mooney, Mikhail
core   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Restricted Randomization versus Blocking

open access: yesInternational Statistical Review / Revue Internationale de Statistique, 1985
La randomisation restreinte peut etre superieure a l'utilisation de blocs artificiels quand on dispose de peu de parcelles. On presente de bonnes methodes de randomisation restreinte pour 2 ou 4 objets repartis en 8 parcelles constituant un rectangle 2 ...
openaire   +2 more sources

Rerandomization to improve covariate balance in experiments

open access: yes, 2012
Randomized experiments are the "gold standard" for estimating causal effects, yet often in practice, chance imbalances exist in covariate distributions between treatment groups.
Morgan, Kari Lock, Rubin, Donald B.
core   +1 more source

Sensor networks and distributed CSP: communication, computation and complexity [PDF]

open access: yes, 2005
We introduce SensorDCSP, a naturally distributed benchmark based on a real-world application that arises in the context of networked distributed systems.
Béjar Torres, Ramón   +6 more
core   +1 more source

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

open access: yesFEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa   +8 more
wiley   +1 more source

Handling Covariates in the Design of Clinical Trials

open access: yes, 2011
There has been a split in the statistics community about the need for taking covariates into account in the design phase of a clinical trial. There are many advocates of using stratification and covariate-adaptive randomization to promote balance on ...
Rosenberger, William F.   +1 more
core   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

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