Results 61 to 70 of about 142,506 (314)

Attractive targeted sugar bait phase III trials in Kenya, Mali, and Zambia

Trials, 2022
Background Long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) target night-time indoor biting mosquitoes and effectively reduce malaria transmission in rural settings across Africa, but additional vector control tools are needed to
Attractive Targeted Sugar Bait Phase III Trial Group
doaj   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Association between dietary zinc intake and epilepsy: findings from NHANES 2013–2018 and a Mendelian randomization study

Frontiers in Nutrition
BackgroundThe association between dietary zinc intake and epilepsy remains unclear. This study aimed to investigate the relationship between zinc intake from the diet and epilepsy, employing Mendelian randomization (MR) to explore potential causal links ...
Shicun Huang, Ya Gao, Yingqi Chen, Yiqing Wang, Yeting Lu, Wei Gao, Xiaowei Hu, Qi Fang   +7 more
doaj   +1 more source

A Randomized Trial of Dietary Sodium Restriction in CKD [PDF]

Journal of the American Society of Nephrology, 2013
There is a paucity of quality evidence regarding the effects of sodium restriction in patients with CKD, particularly in patients with pre-end stage CKD, where controlling modifiable risk factors may be especially important for delaying CKD progression and cardiovascular events.
Judith Bauer, Carmel M. Hawley, Carmel M. Hawley, David W. Johnson, David W. Johnson, Emma McMahon, Nicole M. Isbel, Nicole M. Isbel, Michael Stowasser, Michael Stowasser, Katrina L. Campbell, Katrina L. Campbell   +11 more
openaire   +5 more sources

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Twin-Field Quantum Digital Signature with Fully Discrete Phase Randomization

Entropy, 2022
Quantum digital signatures (QDS) are able to verify the authenticity and integrity of a message in modern communication. However, the current QDS protocols are restricted by the fundamental rate-loss bound and the secure signature distance cannot be ...
Jiayao Wu, Chen He, Jiahui Xie, Xiaopeng Liu, Minghui Zhang   +4 more
doaj   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

Liberal vs. restricted opioid prescribing following midurethral sling dataset

Data in Brief, 2023
Postoperative opioid prescribing has historically lacked information critical to balancing the pain control needs of the individual patient with our professional responsibility to judiciously prescribe these high-risk medications.
Brianne M. Morgan, Jaime B. Long, Sarah S. Boyd, Matthew F. Davies, Allen R. Kunselman, Christy M. Stetter, Michael H. Andreae   +6 more
doaj  

Evaluation of episiotomy in present day obstetric practice

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2020
Background: Episiotomy, a surgically planned incision on the perineum and the posterior vaginal wall during the second stage of labor is one of the most performed surgical procedures in the world, especially for nulliparous women.
Manasi Thakur, Himadri Bal, Vikas Tambe, Nikhila Singireddy   +3 more
doaj   +1 more source

On optimal designs for clinical trials: An updated review [PDF]

, 2019
Optimization of clinical trial designs can help investigators achieve higher qualityresults for the given resource constraints. The present paper gives an overviewof optimal designs for various important problems that arise in different stages ofclinical
Ryeznik, Yevgen, Sverdlov, Oleksandr, Wong, Weng Kee   +2 more
core   +1 more source