Results 171 to 180 of about 19,151,760 (225)

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Concerted Action of Targeted Nucleic Acid Therapeutics as Flexible, Precision and Personalized Cancer Treatment

Advanced Science, EarlyView.
Combinations of small activating RNAs and small interfering RNAs were developed as personalized precision therapies that simultaneously activate tumor suppressors and silence oncogenes according to the molecular signatures of patient tumors. This combination strategy demonstrated superior anticancer efficacy, highlighting the promise of precision ...
Jing Wu, Jiaxuan Chen, Abdechakour Elkihel, Wenjun Lan, Nicolas Fraunhoffer, Dandan Zhu, Baoping Lian, Christina Galanakou, Zhancun Bian, Xi Liu, Odile Gayet, Loic Moubri, Julie Aglietti Roques, Vikash Reebye, Nagy Habib, Xiaoxuan Liu, Nelson Dusetti, Juan Lucio Iovanna, Ling Peng   +18 more
wiley   +1 more source

Design of Photocatalytic Composite Coatings for Formaldehyde Removal Based on the Visual Effects of Wood Furniture

Advanced Science, EarlyView.
This work develops photocatalytic coatings for indoor formaldehyde removal on wood surfaces. It explores coating‐induced color variations and visual perception via eye‐tracking tests. Combined with XGBoost and Bayesian optimization, an intelligent design framework is established to guide the optimization of visually friendly wood photocatalytic ...
Xinyue Wei, Shuyuan Chen, Xinlong Zhou, Han Wang, Wei Guo, Xiaoting Niu, Wei Li, Zhen Ding, Haiyuan Chi   +8 more
wiley   +1 more source

A Robotic Testing Platform for Pipelined Discovery of Resilient Dielectric Elastomer Actuators

Advanced Science, EarlyView.
This work introduces a robotic testing platform enabling high‐throughput, multi‐parameter lifetime mapping of linear dielectric elastomer actuators (DEAs). By integrating programmable high‐voltage control and automated electromechanical measurements, the system identifies material and operating conditions that double actuator lifetime.
Ang (Leo) Li, Alexander Yin, Alexander White, Sahib Sandhu, Anatol Gogoj, Denise Maria de Andrade, Matthew Francoeur, Victor Jimenez‐Santiago, Van Remenar, Codrin Tugui, Mihai Duduta   +10 more
wiley   +1 more source

Performance Estimation and Ex Vivo Validation of Untethered Magnetic Robots in Soft Tissue

Advanced Science, EarlyView.
This study presents an empirical model that quantitatively predicts the step‐out frequency of screw‐type untethered magnetic robots (UMRs) in soft viscoelastic environments, including ex vivo brain tissue. By integrating key parameters into a dimensionless framework, the model enables estimation of robot performance across a range of biological ...
Leendert‐Jan W. Ligtenberg, Thijs J. van der Burg, Stijn Y. Kolkman, Santiago Saavedra Castano, David Fernandez Rivas, Anke Klingner, Roger M. L. M. Lomme, Lucas S. Joziasse, Dorothee Wasserberg, H. Remco Liefers, Doron Ben Ami, Udi Sadeh, Oded Shoseyov, Giulio Dagnino, Pascal Jonkheijm, Jurgen J. Fütterer, Stefano Stramigioli, J. Frank W. Nijsen, Michiel C. Warlé, Islam S. M. Khalil   +19 more
wiley   +1 more source

Large‐Area Noise‐Resilient Multiplexing Triboelectric Biomechanical Sensing on Clothing for High‐Precision Full‐Body Motion Capture in Wearables

Advanced Science, EarlyView.
A large‐area, noise‐resilient multiplexed triboelectric sensing garment based on a multilayer shielded architecture and SnS2 nanoflower‐engineered hybrid materials enables interference‐suppressed, high‐fidelity full‐body motion tracking, achieving 0.13% signal misrecognition, 57 dB electromagnetic noise attenuation, and >1.5 N threshold force, while ...
Beibei Shao, Ming‐Han Lu, Wei‐Chen Peng, Wei‐Chun Yang, Yi‐Ting Chen, Jiun‐Wei Fong, Tzu‐Ching Lu, Tai‐Chen Wu, Zhi‐Xian Yan, Kai‐Yuan Hsiao, Jiann‐Yeu Chen, Ming‐Yen Lu, Heng‐Jui Liu, Ruiyuan Liu, Ying‐Chih Lai   +14 more
wiley   +1 more source

Bio‐Inspired Gradient Coatings Enhance the Leading Edge Erosion Resistance of Wind Blades

Advanced Science, EarlyView.
Rain‐induced erosion of the wind turbine blade leading edge poses a critical challenge to maintenance and operation. Here, we propose a bio‐inspired approach for erosion protection utilising a platelet‐reinforced polyurethane coating with a graded through‐thickness architecture.
Natalia Sofia Guevara‐Sotelo, Julie Teuwen, Kunal Masania   +2 more
wiley   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Root‐Inspired Microneedle Patch With Interlocked Rigid‐Soft Architecture for High Tissue‐Adaptiveness

Advanced Science, EarlyView.
A root‐inspired microneedle array patch uses lattice‐based mechanical interlocking to unite rigid microneedles with a flexible substrate. The interlocked rigid–soft architecture improves interfacial bonding, supports stable adhesion on curved and wet tissues under dynamic motion, and provides a versatile platform for robust biointerfacing and future ...
Jongchan Lee, Yeongjun Song, Yonghyun Cho, Hyo In Kim, Dong‐Hyun Youn, Jinbong Park, Seungbeom Choi, Dohyun Kwon, Brian Jun Lee, Sangyul Baik   +9 more
wiley   +1 more source