Results 201 to 210 of about 605,403 (299)

Modular organization of related Archaeal plasmids encoding different restriction-modification systems inMethanobacterium thermoformicicum

, 1992
Jörk Nölling, Fredericus J. M. van Eeden, Rik I.L. Eggen, Willem M. de Vos   +3 more
openalex   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Optimising Transformation Efficiency in Borrelia: Unravelling the Role of the Restriction-Modification System of Borrelia afzelii and Borrelia garinii. [PDF]

Int J Mol Sci
Ruivo M, Kovács NZ, Schötta AM, Stelzer T, Hermann L, Mündler V, Bergthaler A, Reiter M, Wijnveld M.   +8 more
europepmc   +1 more source

Diversification of the restriction–modification system ofStreptococcus pyogenesthrough its acquisition of mobile elements [PDF]

, 2020
Atsushi Ota, Yukiko Nishiuchi, Noriko Nakanishi, Yoshio Iijima, Tomotada Iwamoto, Ken Osaki, Yoshitoshi Ogura, Atsushi Toyoda, Yutaka Suzuki, Tetsuya Hayashi, Hiroki Ohge, Hirotada Mori, Manabu Ato, Fumito Maruyama   +13 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Characterization of a Novel N4-Methylcytosine Restriction-Modification System in Deinococcus radiodurans. [PDF]

Int J Mol Sci
Shi C, Wang L, Xu H, Zhao Y, Tian B, Hua Y.   +5 more
europepmc   +1 more source

Additional file 7: Table S1. of Pangenome analysis of Bifidobacterium longum and site-directed mutagenesis through by-pass of restriction-modification systems

, 2015
A. O’Callaghan, Francesca Bottacini, M. O’Connell Motherway, Douwe van Sinderen   +3 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Effect of restriction-modification systems on transfer of foreign DNA into Lactococcus lactis subsp. lactis [PDF]

, 1989
Philippe Langella
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source