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Integrated Microdevice for DNA Restriction Fragment Analysis

Analytical Chemistry, 1996
An integrated monolithic device (8 mm × 10 mm) that performs an automated biochemical procedure is demonstrated. The device mixes a DNA sample with a restriction enzyme in a 0.7-nL reaction chamber and after a digestion period injects the fragments onto a 67-mm-long capillary electrophoresis channel for sizing. Materials are precisely manipulated under
S C, Jacobson, J M, Ramsey
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Restriction fragment analysis of somaclones

1991
Somaclonal variation is a feature common to all plant regeneration via a tissue culture or ‘callus’ phase [7, 10]. Whether the intention is to maximise variation (for production of variability in plant breeding) or minimise it (to reduce variability in mass propagation systems or transformation studies) it is very important to be able to identify ...
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Restriction Fragment Analysis

1992
Arndt Rolfs +3 more
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Monodisperse DNA restriction fragments