FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Molecular typing of canine parvovirus type 2 by VP2 gene sequencing and restriction fragment length polymorphism in affected dogs from Egypt. [PDF]
Front Microbiol, 2023 Magouz A +8 more
europepmc +1 more source
Use of restriction fragment length polymorphisms (RFLPs) to distinguish between nematodes of pathogenic significance [PDF]
, 1988 The availability of restriction fragment length polymorphisms (RFLPs) would be useful for studying the extent of diversity among morpholgically indistinguishable populations of filarial parasites. Such polymorphisms may be useful in correlating various
Cameron, M L +5 more
core
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
UGT1A1 gene and neonatal hyperbilirubinemia: a preliminary study from Bengkulu, Indonesia
BMC Research Notes, 2018 Objective The genetic involvement in unconjugated neonatal hyperbilirubinemia has been extensively studied. Despite the high incidence of hyperbilirubinemia in Indonesia, studies are lacking.
Radhian Amandito +6 more
doaj +1 more source
Analisis Keanekaragaman Kultivar Pisang Menggunakan Penanda Pcr-rflp Pada Internal Transcribed Spacer (Its) Dna Ribosom [PDF]
, 2012 Pisang merupakan bahan makanan pokok keempat terpenting di negara berkembang yang memiliki keanekaragaman sangat tinggi. Penanda DNA mikrosatelit dapat membedakan kultivar pisang yang memiliki genom A dengan kultivar pisang bergenom B.
Ekasari, T. W. (T) +2 more
core
FEBS Open Bio, EarlyView.Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey +2 more
wiley +1 more source
Comparison of PCR-RFLP pattern with sequencing analysis of the ITS region of Hyrcanain\'s Tilia
تاکسونومی و بیوسیستماتیک, 2014 Sequencing of ITS region is one of the candidate markers as a DNA barcoding in Plants. Since sequencing technique is expensive and time consuming, we used PCR-RFLP technique and compared the result of these methods (PCR-RFLP and sequencing) to evaluate ...
Hamed Yousefzadeh +2 more
doaj
A Novel 16S rRNA PCR-Restriction Fragment Length Polymorphism Assay to Accurately Distinguish Zoonotic Capnocytophaga canimorsus and C. cynodegmi. [PDF]
Microbiol Spectr, 2023 Lai CH +4 more
europepmc +1 more source
restriction fragment length polymorphism
Citation: 'restriction fragment length polymorphism' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09723 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual ...
openaire +1 more source