Results 1 to 10 of about 2,423,969 (313)

Rapid SNP discovery and genetic mapping using sequenced RAD markers. [PDF]

open access: yesPLoS ONE, 2008
Single nucleotide polymorphism (SNP) discovery and genotyping are essential to genetic mapping. There remains a need for a simple, inexpensive platform that allows high-density SNP discovery and genotyping in large populations.
Nathan A Baird   +8 more
doaj   +2 more sources

Optical Whole-Genome Restriction Mapping as a Tool for Rapidly Distinguishing and Identifying Bacterial Contaminants in Clinical Samples [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2015
Introduction: Optical restriction genome mapping is a technology in which a genome is linearized on a surface and digested with specific restriction enzymes, giving an arrangement of the genome with gaps whose order and size are unique for a given ...
Richard R. Chapleau, James C. Baldwin
doaj   +2 more sources

A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping and DNA sequence data. III. Cladogram estimation. [PDF]

open access: bronzeGenetics, 1992
We previously developed a cladistic approach to identify subsets of haplotypes defined by restriction endonuclease mapping or DNA sequencing that are associated with significant phenotypic deviations.
Alan R. Templeton   +2 more
openalex   +2 more sources

Molecular Mapping of Restriction-Site Associated DNA Markers In Allotetraploid Upland Cotton.

open access: yesPLoS ONE, 2015
Upland cotton (Gossypium hirsutum L., 2n = 52, AADD) is an allotetraploid, therefore the discovery of single nucleotide polymorphism (SNP) markers is difficult. The recent emergence of genome complexity reduction technologies based on the next-generation
Yangkun Wang   +8 more
doaj   +2 more sources

Heterogeneity in type I Gaucher disease demonstrated by restriction mapping of the gene.

open access: greenProceedings of the National Academy of Sciences of the United States of America, 1985
A cloned fragment of human glucocerebrosidase cDNA has been used as a probe to study restriction polymorphisms in the region of the gene for Gaucher disease.
Joseph A. Sorge   +4 more
openalex   +2 more sources

Molecular cloning, sequencing and restriction mapping of the genomic sequence encoding human proacrosin [PDF]

open access: bronzeEuropean Journal of Biochemistry, 1992
In the present study, molecular cloning, sequencing and restriction mapping of the genomic sequence encoding human proacrosin is described. The full-length cDNA encoding human proacrosin was utilized to recover a 17-kb human genomic clone which was ...
Mónica H. Vazquez‐Levin   +2 more
openalex   +2 more sources

Endonuclease-Mediated Long PCR and Its Application to Restriction Mapping [PDF]

open access: goldCurrent Issues in Molecular Biology, 1999
The polymerase chain reaction (PCR) is the most widely used technique for the study of DNA. Applications for PCR have been extended significantly by the development of "long" PCR, a technique that makes it possible to amplify DNA fragments up to 40 kb in
Chengtao Her, R. M. Weinshilboum
openalex   +2 more sources

Combining Linkage and Association Mapping Approaches to Study the Genetic Architecture of Verticillium Wilt Resistance in Sunflower [PDF]

open access: yesPlants
Sunflower Verticillium Wilt and Leaf Mottle (SVW), caused by Verticillium dahliae Kleb., is a globally prevalent disease affecting sunflower production.
Juan F. Montecchia   +14 more
doaj   +2 more sources

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