Results 1 to 10 of about 2,063,201 (347)

Rapid SNP discovery and genetic mapping using sequenced RAD markers. [PDF]

open access: yesPLoS ONE, 2008
Single nucleotide polymorphism (SNP) discovery and genotyping are essential to genetic mapping. There remains a need for a simple, inexpensive platform that allows high-density SNP discovery and genotyping in large populations.
Nathan A Baird   +8 more
doaj   +2 more sources

Optical Whole-Genome Restriction Mapping as a Tool for Rapidly Distinguishing and Identifying Bacterial Contaminants in Clinical Samples [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2015
Introduction: Optical restriction genome mapping is a technology in which a genome is linearized on a surface and digested with specific restriction enzymes, giving an arrangement of the genome with gaps whose order and size are unique for a given ...
Richard R. Chapleau, James C. Baldwin
doaj   +2 more sources

Restriction mapping in nanofluidic devices [PDF]

open access: yesProceedings of the National Academy of Sciences, 2005
We have performed restriction mapping of DNA molecules using restriction endonucleases in nanochannels with diameters of 100-200 nm. The location of the restriction reaction within the device is controlled by electrophoresis and diffusion of Mg 2+ and EDTA.
Robert, Riehn   +5 more
openaire   +3 more sources

Methodological landscape in the field of integration site identification of retroviruses and retroviral vectors [PDF]

open access: yesFrontiers in Bioengineering and Biotechnology
Detailed mapping of viral vector integration sites, including retroviral and particularly lentiviral vectors, is critical for assessing their safety in preclinical and clinical studies.
Konstantin Kochergin-Nikitsky   +2 more
doaj   +2 more sources

Molecular Mapping of Restriction-Site Associated DNA Markers In Allotetraploid Upland Cotton.

open access: yesPLoS ONE, 2015
Upland cotton (Gossypium hirsutum L., 2n = 52, AADD) is an allotetraploid, therefore the discovery of single nucleotide polymorphism (SNP) markers is difficult. The recent emergence of genome complexity reduction technologies based on the next-generation
Yangkun Wang   +8 more
doaj   +2 more sources

The restriction mapping problem revisited

open access: yesJournal of Computer and System Sciences, 2002
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Pandurangan, Gopal, Ramesh, H
openaire   +4 more sources

In Silico Restriction Enzyme Digests to Minimize Mapping Bias in Genomic Sequencing [PDF]

open access: goldMolecular Therapy: Methods & Clinical Development, 2017
Jason Roszik   +4 more
doaj   +2 more sources

A novel method for effectively selecting fragments not associated with restriction sites for whole-genome genotyping [PDF]

open access: yesBMC Biology
Background Reduced representation sequencing (RRS) using Restriction site-associated DNA sequencing (RAD-seq) has become a widely adopted method for whole-genome genotyping, owing to its cost-effectiveness and applicability across species.
Peng Chen   +9 more
doaj   +2 more sources

DNA Mapping Algorithms: Strategies for Single Restriction Enzyme and Multiple Restriction Enzyme Mapping

open access: green, 1992
An approach to high-resolution restriction-fragment DNA mapping, known as Multiple-Restriction-Enzyme mapping (MRE mapping), is present. This approach significantly reduces the uncertainty of clone placement by using clone ends to synchronize the position in of clones within different maps, each map being constructed from fragment-length data produced ...
Will Gillett
openalex   +4 more sources

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