Results 161 to 170 of about 1,719,518 (302)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Hodgson Downs, Northern Territory [cartographic material] : Commonwealth topographic survey /

open access: yes, 1960
Provisional ed. Topographic map of Hodgson Downs, Northern Territory showing classes of roads, railway and telephone lines, mines, post offices, wireless transceivers, windpumps, airports or airfields and landing grounds, horizontal control points ...
Australia. Division of National Mapping.
core  

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Haiti 1:50,000 [cartographic material] /

open access: yes, 1948
Geographic coverage complete in 81 sheets.; Map series of Haiti and Navassa Island. Relief shown by contours and spot heights. Depths shown by contours and soundings on some sheets.; Earlier sheets prepared by Army Map Service; Defense Mapping Agency ...
United States. National Imagery and Mapping Agency.
core  

In Silico Restriction Enzyme Digests to Minimize Mapping Bias in Genomic Sequencing

open access: yesMolecular Therapy: Methods & Clinical Development, 2017
Jason Roszik   +4 more
doaj   +1 more source

Revisiting the foundation era of plant genomics with a commentary on the pioneering contributions of Prof. Chittaranjan Kole. [PDF]

open access: yesPlant Genome
Nageswara-Rao M   +23 more
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

open access: yesFEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual   +3 more
wiley   +1 more source

Henbury, Northern Territory [cartographic material] : Commonwealth Topographic Survey /

open access: yes, 1960
Provisional ed. Topographic map of Henbury region, Northern Territory, showing classes of roads, railway and telephone lines, fences, state boundries, watercourses and dams, and windpumps. Relief shown by spot heights.; "Compilation: Division of National
Australia. Division of National Mapping.
core  

Novel Strategy for Structural Variant Genotyping by Short-Read Genomic Sequencing From Restriction-Circles: Experimental and Bioinformatics Proof-of-Concept. [PDF]

open access: yesHum Mutat
Abelleyro MM   +8 more
europepmc   +1 more source

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