Results 171 to 180 of about 1,719,518 (302)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Diet-responsive proteogenomic effects following short-term restriction of animal products in humans. [PDF]

Nat Commun
Simistiras A, Bocher O, Emmanouil C, Skoulakis A, Glentis S, Scarmeas N, Zeggini E, Rouskas K, Dimas AS.   +8 more
europepmc   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Proteome-wide curation of experimentally validated HPV T-cell epitopes identifies key gaps in our understanding of cellular immunity to HPV and informs vaccine design. [PDF]

Front Immunol
Putra SP, Cankat S, Swadling L.
europepmc   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Delamere, Northern Territory [cartographic material] : Commonwealth topographic survey /

, 1960
Provisional ed. Topographic map of Delamere, Northern Territory showing classes of roads, railway and telephone lines, mines, post offices, wireless transceivers, windpumps, airports or airfields and landing grounds, horizontal control points ...
Australia. Division of National Mapping.
core  

Assessment of LLMs on basic bioinformatics tasks requiring multi-step reasoning and code writing. [PDF]

Bioinformatics
Rajesh V, Blumberg M, Jain S, Siwo GH.
europepmc   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Lake Amadeus, Northern Territory [cartographic material] : Commonwealth Topographic Survey /

, 1961
Provisional ed. Topographic map of Lake Amadeus region, Northern Territory, showing classes of roads, railway and telephone lines, fences, state boundries, watercourses and dams, and windpumps.
Australia. Division of National Mapping.
core