Optical Whole-Genome Restriction Mapping as a Tool for Rapidly Distinguishing and Identifying Bacterial Contaminants in Clinical Samples [PDF]
Journal of Clinical and Diagnostic Research, 2015 Introduction: Optical restriction genome mapping is a technology in which a genome is linearized on a surface and digested with specific restriction enzymes, giving an arrangement of the genome with gaps whose order and size are unique for a given ...
Richard R. Chapleau, James C. Baldwin
doaj +2 more sources
Methodological landscape in the field of integration site identification of retroviruses and retroviral vectors [PDF]
Frontiers in Bioengineering and BiotechnologyDetailed mapping of viral vector integration sites, including retroviral and particularly lentiviral vectors, is critical for assessing their safety in preclinical and clinical studies.
Konstantin Kochergin-Nikitsky +2 more
doaj +2 more sources
In Silico Restriction Enzyme Digests to Minimize Mapping Bias in Genomic Sequencing [PDF]
Molecular Therapy: Methods & Clinical Development, 2017 Jason Roszik +4 more
doaj +2 more sources
, 1992 An approach to high-resolution restriction-fragment DNA mapping, known as Multiple-Restriction-Enzyme mapping (MRE mapping), is present. This approach significantly reduces the uncertainty of clone placement by using clone ends to synchronize the position in of clones within different maps, each map being constructed from fragment-length data produced ...
Will Gillett
openalex +4 more sources
Antigenic and Genetic Characterization of Twenty-six Strains of Human Respiratory Syncytial Virus (Subgroup A) Isolated During Three Consecutive Outbreaks in Havana City, Cuba [PDF]
Memorias do Instituto Oswaldo Cruz, 1999 Twenty-six human respiratory syncytial virus strains (subgroup A) isolated from three outbreaks in Havana City during the period 1994/95, 1995/96 and 1996/97 were analyzed to determine their antigenic and genetic relationships. Analyses were performed by
Angel Valdivia +10 more
doaj +1 more source
Rapid SNP discovery and genetic mapping using sequenced RAD markers. [PDF]
PLoS ONE, 2008 Single nucleotide polymorphism (SNP) discovery and genotyping are essential to genetic mapping. There remains a need for a simple, inexpensive platform that allows high-density SNP discovery and genotyping in large populations.
Nathan A Baird +8 more
doaj +1 more source
A database of restriction maps to expand the utility of bacterial artificial chromosomes
GigaByte, 2023 While Bacterial Artificial Chromosomes libraries were once a key resource for the genomic community, they have been obviated, for sequencing purposes, by long-read technologies.
Eamon Winden +5 more
doaj +1 more source
On $F$-Weak Contraction of Generalized Multivalued Integral Type Mappings with $alpha $-admissible [PDF]
Sahand Communications in Mathematical Analysis, 2020 The purpose of this work is to investigate the existence of fixed points of some mappings in fixed point theory by combining some important concepts which are F-weak contractions, multivalued mappings, integral transformations and α-admissible mappings ...
Vatan Karakaya +2 more
doaj +1 more source
The use of the hypervariable P8 region of trnL(UAA) intron for identification of orchid species: Evidence from restriction site polymorphism analysis. [PDF]
PLoS ONE, 2018 The P8 stem-loop region of the trnL intron, which is known to be hypervariable in size with multiple repeat motifs and created difficulties in alignment, is always excluded in phylogenetic as well as barcode analyses.
Rajkumar Kishor, G J Sharma
doaj +1 more source
Biochemistry and Molecular Biology Education, 2002 AbstractTerms to be familiar with before you start to solve the test: restriction endonucleases, DNA polymerase, exonucleases, agarose gel electrophoresis, autoradiography, DNA synthesis.
openaire +2 more sources